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TranscriptomicsIdentification of a microRNA regulator for axon guidance in the olfactory bulb of adult mice
Using the highly sensitive miRNA array, we screened 40 microRNAs abundant in the olfactory bulb and we explored the functions of these miRNAs in the olfactory bulb by Gene Ontology and Kyoto Encyclopedia of Genes annotation. The enrichment results indicated that these miRNAs mainly participated in t...
ORGANISM(S): Mus musculus 
2014-08-27 | E-GEOD-55463 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila mutant and wild type embryos toinvestigate axon guidance
During the development of the Drosophila central nervous system the process of midline crossing is orchestrated by a number of guidance receptors and ligands. Many key axon guidance molecules have been identified in both invertebrates and vertebrates, but the transcriptional regulation of growth co...
ORGANISM(S): Drosophila melanogaster 
2008-06-15 | E-GEOD-6515 | biostudies-arrayexpress
GenomicsPolarized Dock Activity Drives Shh-Mediated Axon Guidance
Polarized Dock Activity Drives Shh-Mediated Axon Guidance
PRJNA1118019 | ENA
TranscriptomicsAxon Guidance Receptor ROBO3 Modulates Subtype Identity and Prognosis via AXL-associated Inflammatory Network in Pancreatic Cancer
Recently, genome-wide molecular analyses have identified an altered axon guidance SLIT-ROBO signaling pathway in Pancreatic ductal adenocarcinoma (PDAC). To examine whether ROBO3 signaling is involved in the transcriptional determination of basal-like PDAC-subtype specification and functions, we per...
ORGANISM(S): Homo sapiens 
2022-07-31 | E-MTAB-11476 | biostudies-arrayexpress
GenomicsMidline Assembloids Reveal Regulators of Human Axon Guidance
Midline Assembloids Reveal Regulators of Human Axon Guidance
PRJNA1119448 | ENA
UnknownNoncanonical Notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of Trio.
Not available
S-EPMC3070923 | biostudies-literature
TranscriptomicsCHD7 regulates gene networks involved in neural crest cell migration and axon guidance
Heterozygous loss-of function mutations in CHD7 (chromodomain helicase DNA-binding protein 7) lead to CHARGE syndrome, a complex developmental disorder affecting craniofacial structures, peripheral nerves and several organ systems like eyes, ears, nose and heart. Recently, it was demonstrated that C...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-46591 | biostudies-arrayexpress
TranscriptomicsAxon Guidance Study in Drosophila embryos
During the development of the Drosophila central nervous system the process of midline crossing is orchestrated by a number of guidance receptors and ligands. Many key axon guidance molecules have been identified in both invertebrates and vertebrates, but the transcriptional regulation of growth con...
ORGANISM(S): Drosophila melanogaster 
2006-12-14 | GSE6515 | GEO
TranscriptomicsAnnexin A2 controls pancreatic cancer invasion and metastasis through a novel axon guidance pathway
The mechanisms involved in promoting metastasis of pancreatic ductal adenocarcinoma have yet to be elucidated. Here, we show that AnnexinA2 regulates the secretion of Semaphorin3D from pancreatic tumor cells allowing it to bind to its receptor PlexinD1 on the surface of the tumor cell, which induces...
ORGANISM(S): Mus musculus 
2015-09-03 | E-GEOD-62285 | biostudies-arrayexpress
GenomicsTet Controls Axon Guidance in Early Brain Development through Glutamatergic Signaling
Tet Controls Axon Guidance in Early Brain Development through Glutamatergic Signaling
PRJNA966247 | ENA
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