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The knowledge regarding toxins diversity, composition, structure, molecular and pharmacological interactions involved in the process of envenomation provide lessons for drug design based on these natural molecular scaffolds and pharmacophores of toxins. This study unravels new toxins sequenced by ma...
ORGANISM(S): Bothrops cotiara 
2023-10-20 | PXD041473 | Pride
The knowledge regarding toxins diversity, composition, structure, molecular and pharmacological interactions involved in the process of envenomation provide lessons for drug design based on these natural molecular scaffolds and pharmacophores of toxins. This study unravels new toxins sequenced by ma...
ORGANISM(S): Bothrops cotiara 
2023-10-20 | PXD036130 | Pride
In our study, we applied high-throughput mass spectrometry, bioinformatic, and machine learning approaches to investigate the proteome, including noncoding RNA (ncRNA)–derived micropeptides, of different breast cancer subtypes. In total, 19 tumor and 18 paired nontumor samples were used to obtain th...
ORGANISM(S): Homo sapiens (Human) 
2024-11-12 | PXD057759 | Pride
Snake venoms have evolved in a few families of Caenophidae, and their toxins have been fine-tuned over the evolutive process into highly effective biochemical weapons with a particular role as a trophic adaptation. However, there are many outstanding questions on how venom contributes to the success...
ORGANISM(S): Bothrops bilineatus Bothrocophias hyoprora Bothrops atrox Bothrops taeniatus Bothrops brazili 
2024-05-24 | PXD046872 | Pride
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