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GenomicsWhole-genome mapping of ETV6-RUNX1 in pre-B lymphoblast models
Whole-genome mapping of ETV6-RUNX1 in pre-B lymphoblast models
PRJNA734856 | ENA
TranscriptomicsGene expression profiling of the response to interferon beta in EBV-transformed and primary B cells of patients with multiple sclerosis
To identify gene expression changes and pathways induced by interferon-? (IFN-?) in B cells, we studied the in vitro response of EBV-transformed B cells (lymphoblast cell lines-LCLs). LCLs were derived from an MS patient repository. Whole genome expression analysis identified 115 genes that were mor...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-58240 | biostudies-arrayexpress
UnknownAn Aggregated-Based Deep Learning Method for Leukemic B-lymphoblast Classification.
Not available
S-EPMC7763941 | biostudies-literature
GenomicsWhole-genome mapping of RUNX1, CBFA2T3, H3K4me1, H3K4me3, H3k27me3 and H3K27ac in pre-B lymphoblast models
Whole-genome mapping of RUNX1, CBFA2T3, H3K4me1, H3K4me3, H3k27me3 and H3K27ac in pre-B lymphoblast models
PRJNA482944 | ENA
UnknownSustained remission with azacitidine monotherapy and an aberrant precursor B-lymphoblast population in juvenile myelomonocytic leukemia.
Not available
S-EPMC7328527 | biostudies-literature
GenomicsNK co-culture CRISPR screen in the 721.221 B-cell lymphoblast
NK co-culture CRISPR screen in the 721.221 B-cell lymphoblast
PRJNA948455 | ENA
TranscriptomicsTranscription profiling of human lymphoblast cell lines from 13 unrelated index patients and siblings
Recessive retinitis pigmentosa (RP) is often caused by nonsense mutations that lead to low mRNA levels as a result of nonsense-mediated decay. Some RP genes are expressed at detectable levels in leukocytes as well as in the retina. We designed a microarray-based method to find recessive RP genes bas...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-12086 | biostudies-arrayexpress
GenomicsSingle-cell RNA sequencing of primary human B-cell acute lymphoblast leukemia (ALL) cells
Single-cell RNA sequencing of primary human B-cell acute lymphoblast leukemia (ALL) cells
PRJNA682097 | ENA
TranscriptomicsGenome Wide Analysis of Immune Activation in Human T and B Cells Reveals Distinct Classes of Alternatively Spliced Genes
Alternative splicing of pre-mRNA is a mechanism that increases the protein diversity of a single gene by differential exon inclusion during post-transcriptional processing. While alternative splicing is established to occur during lymphocyte activation, little is known about the role it plays during...
ORGANISM(S): Homo sapiens 
2010-04-08 | E-GEOD-14352 | biostudies-arrayexpress
GenomicsEpstein-Barr Virus Exploits Intrinsic B-Lymphocyte Transcription Programs to Achieve Immortal Cell Growth
Epstein-Barr Virus Nuclear Antigen 2 (EBNA2) gene regulation through the cell RBPJ transcription factor (TF) is essential for conversion of resting B-lymphocytes (RBLs) into Lymphoblastoid Cell Lines (LCLs). ChIP-seq investigation of EBNA2 and RBPJ sites in LCL DNA found EBNA2 at 5151 and RBPJ at 10...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-29498 | biostudies-arrayexpress
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