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MetabolomicsMetabolomics of human primary B-ALL cells treated by BCR-Abl1 inhibitor, STI571, and p190 BCR-Abl+ BAF3 cells with ASS1 knockdown
Analyze the Metabolomics changes in B-ALL cells after the treatment of imatinib and p190+ BAF3 cells with ASS1 knockdown or left untreated. two methods as the below LC-MS description showed were used.
2026-07-08 | MTBLS14638 | MetaboLights
TranscriptomicsRNA-seq of primary human bone marrow derived mesenchymal stromal cells from pediatric B-cell acute lymphoblastic leukemia (B-ALL) patients
To investigate the identity of the tumor microenvironment in acute lymphoblastic leukemia (B-ALL), the transcriptome of mesenchymal stromal cells derived from bone marrow of three pediatric patients at the onset of the disease was analyzed and compared with its normal counterpart.
ORGANISM(S): Homo sapiens 
2021-10-16 | E-MTAB-10838 | biostudies-arrayexpress
GenomicsRNA-seq of B-ALL patients
RNA-seq of B-ALL patients
PRJEB50451 | ENA
GenomicsChip-seq of B-ALL patients
Chip-seq of B-ALL patients
PRJEB51301 | ENA
GenomicsChip-seq of B-ALL patients
Chip-seq of B-ALL patients (H3K27, H3K4)
ORGANISM(S): Homo sapiens 
2024-01-01 | E-MTAB-11500 | biostudies-arrayexpress
TranscriptomicsRole of miR-125b in B-cell acute lymphoblastic leukemia (B-ALL)
B-cell acute lymphoblastic leukemia (B-ALL) is often associated with chromosomal translocations leading to the deregulation of proto-oncogenes. MicroRNAs can also be affected by chromosomal alterations and thus contribute to carcinogenesis. The microRNA miR-125b-1 is over-expressed in B-ALL cases wi...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-30647 | biostudies-arrayexpress
GenomicsRole of PTEN in B-ALL
Role of PTEN in B-ALL
PRJNA650503 | ENA
ProteomicsIFITM3 BioID Interactomes in B-ALL and MCL
To determine the roles of membrane associated IFITM3 in BCR-signalling in B-cell malignancies we expressed N-terminal BirA-IFITM3-Y20E fusion or BirA-EV control in patient derived B-ALL cells (PDX2) and Jeko1 Mantle cell lymphoma (MCL) cells. Additionally to examine the role of PIP3 binding residues...
ORGANISM(S): Homo sapiens (Human) 
2020-12-18 | PXD020697 | Pride
Human b-all mcl b-cells 
TranscriptomicsThe Methylome Landscape of Infant B-cell precursor Acute Lymphoblastic Leukemia (iB-ALL)
B-cell acute lymphoblastic leukemia (B-ALL) is the most prevailing childhood cancer. As predicated by its prenatal origin, infant B-ALL (iB-ALL) show a silent mutational landscape irrespective of the MLL rearrangement/status, suggesting that other regulatory mechanisms might be impaired in the conte...
ORGANISM(S): Homo sapiens 
2021-03-12 | E-MTAB-8505 | biostudies-arrayexpress
GenomicsAberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL]
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL]
PRJNA475683 | ENA
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