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TranscriptomicsEvaluation of covS polymorphisms on group A streptococcal global gene expression
We sought to determine how single amino acid changes in the active site of CovS autophosphorylation and subsequent phosphorylation of the response regulator CovR affect the gene expression profile of group A streptococcus There were 6 strains analyzed, each in quadruplicate replicates: 1) wild-type ...
ORGANISM(S): Streptococcus sp. 'group A' 
2015-01-24 | E-GEOD-65226 | biostudies-arrayexpress
TranscriptomicsA Genome-wide Chronological Study of Gene Expression and Two Histone Modifications, H3K4me3 and H3K9ac, during Developmental Leaf Senescence [RNA-seq]
The genome-wide abundance of two histone modifications, H3K4me3 and H3K9ac, both associated with actively expressed genes, was monitored in Arabidopsis thaliana leaves at different time points during developmental senescence, along with expression in the form of RNA-seq data. H3K9ac and H3K4me3 mark...
ORGANISM(S): Arabidopsis thaliana 
2015-04-11 | E-GEOD-67777 | biostudies-arrayexpress
UnknownBiallelic NDUFA4 Deletion Causes Mitochondrial Complex IV Deficiency in a Patient with Leigh Syndrome.
Not available
S-EPMC11050323 | biostudies-literature
UnknownInflammatory Networks in Renal Cell Carcinoma.
Not available
S-EPMC10136567 | biostudies-literature
TranscriptomicsThe CLE40 and CRN/CLV2 signaling pathways antagonistically control root meristem growth in Arabidopsis
Differentiation processes in the primary root meristem are controlled by several signaling pathways that are regulated by phytohormones or by secreted peptides. Long term maintenance of an active root meristem requires that the generation of new root meristem cells and the loss of cells from the mer...
ORGANISM(S): Arabidopsis thaliana 
2014-10-02 | E-GEOD-59167 | biostudies-arrayexpress
UnknownNonparametric Analysis of Thermal Proteome Profiles Reveals Novel Drug-binding Proteins.
Not available
S-EPMC6885700 | biostudies-literature
TranscriptomicsCompensatory cis-trans regulation of mouse liver gene expression
Two inbred mouse strains, C57BL/6J and CAST/EiJ, were crossed to generate both initial and reciprocal F1 crosses. For each genetically distinct class of mice (F0 C57BL/6J, F0 CAST/EiJ, F1i - C57BL/6J x CAST/EiJ, F1r - CAST/EiJ x C57BL/6J, where the male parent is listed first), samples were collecte...
ORGANISM(S): Mus musculus 
2012-09-07 | E-MTAB-1091 | biostudies-arrayexpress
UnknownMinimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets.
Not available
S-EPMC9952969 | biostudies-literature
TranscriptomicsRNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated
Radiotherapy (RT) destroys tumor cells, which may lead to release of antigens and immune-activating signals. In this way, RT may act as an in situ vaccine and kick-start a T-cell response against the tumor. Immunotherapy enhances tumor-specific T-cell responses. Combination of radiotherapy and immun...
ORGANISM(S): Mus musculus 
2019-02-12 | E-MTAB-6914 | biostudies-arrayexpress
GenomicsPersistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions
The androgen receptor (AR) is a ligand-inducible transcription factor that mediates androgen action in target tissues. Upon ligand binding, the AR binds to thousands of genomic loci and activates a cell-type specific gene program. Prostate cancer growth and progression depend on androgen-induced AR ...
ORGANISM(S): Homo sapiens 
2012-10-02 | E-GEOD-40050 | biostudies-arrayexpress
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