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TranscriptomicsRegulation of gene expression in murine liver by IL-6
STEAP4 is a plasma membrane metallo-reductase involved in the transport of iron and copper. Recently, STEAP4 was implicated in promoting insulin sensitivity by acting in white adipose tissue (WAT) to control the production of inflammatory cytokines such as IL-6. Indeed, the loss of STEAP4 expression...
ORGANISM(S): Mus musculus 
2010-04-08 | E-GEOD-21060 | biostudies-arrayexpress
TranscriptomicsHigh natural gene expression variation in the reef-building coral Acropora millepora: Potential for acclimative and adaptive plasticity
This experiment assessed the natural gene expression variation present between colonies of the Indo-Pacific reef-building coral Acropora millepora, and additionally explored whether gene expression differed between two different intron haplotypes according to intron 4-500 in a carbonic anhydrase hom...
ORGANISM(S): Acropora millepora 
2013-04-08 | E-GEOD-42684 | biostudies-arrayexpress
ProteomicsTime course treatment with Palmitate and thapsigargin of insulinoma INS-1E cells
Time course treatment with 0.4 mM Palmitate and 200 nM thapsigargin of insulinoma INS-1E cells. Timepoints; 0, 4, 16 and 24h in biological duplicates within an iTRAQ 8 set for palmitate and thapsigargin, respectively.
ORGANISM(S): Rattus Rattus (black Rat) 
2020-08-18 | PXD020851 | JPOST Repository
ProteomicsFactor H and related proteins in AMD
Age-related macular degeneration (AMD) is a common form of adult blindness. Risk of developing AMD is strongly linked to genetics, in particular at the Regulators of Complement Activation (RCA) locus on Chr1, which contains 6 genes, Complement Factor H (CFH) and Complement Factor H-related 1-5 (CFHR...
ORGANISM(S): Homo Sapiens 
2022-01-18 | PXD023466 | panorama
TranscriptomicsTranscription profiling of mouse lung from wildtype and glucocorticoid recepter knockouts to investigate investigate the role of glucocorticoids in fetal lung development
The aim of this experiment is to investigate the role of glucocorticoids in fetal lung development in more detail.
ORGANISM(S): Mus musculus 
2007-05-31 | E-MEXP-861 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor EGL-5::GFP Binding Regions in L3
modENCODE_submission_3159 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-03-31 | E-GEOD-25796 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor PHA-4::GFP Binding Regions in YA
modENCODE_submission_3161 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-03-31 | E-GEOD-25799 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor SKN-1::GFP Binding Regions in L1
modENCODE_submission_2622 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25810 | biostudies-arrayexpress
TranscriptomicsNotch1 - WISP1 Axis Determines Tumor-Regulating Role of Melanoma Stromal Fibroblasts
Cancer-associated fibroblasts (CAF) are crucial in regulating cancer progression, yet the molecular mechanisms that determine the tumor-regulating function of CAF are poorly understood. Here, we uncover the Notch1 pathway as a molecular determinant that controls the regulatory role of CAF in mela...
ORGANISM(S): Mus musculus 
2016-05-29 | E-GEOD-65316 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor MEP-1::GFP Binding Regions in Embryos
modENCODE_submission_2600 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25800 | biostudies-arrayexpress
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