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TranscriptomicsThe CRE1 carbon catabolite repressor of the fungus Trichoderma reesei: a master regulator of carbon assimilation
The identification and characterization of the transcriptional regulatory networks governing the physiological behaviour and adaptation of microbial cells is a key step in understanding their behaviour. One such wide-domain regulatory circuit, essential to all cells, is carbon catabolite repression ...
ORGANISM(S): Hypocrea jecorina 
2011-06-01 | E-GEOD-21072 | biostudies-arrayexpress
MetabolomicsHypoxia Dependent Inhibition of Glioblastoma Cell Proliferation, Invasion, and Metabolism by the Choline-Kinase Inhibitor JAS239
Background: Elevated choline kinase alpha (ChoK) levels are observed in most solid tumors, including glioblastomas (GBM), and ChoK inhibitors have demonstrated limited efficacy in GBM models. Given that hypoxia is associated with resistance to GBM therapy, we hypothesized that tumor hypoxia c...
2024-06-18 | MTBLS6212 | MetaboLights
TranscriptomicsWidespread transcriptional changes preempt the critical pelagic-benthic transition in the vetigastropod Haliotis asinina
Larval settlement and metamorphosis is a vital transition period for marine invertebrates and can have far-reaching effects on the ecology and evolution of a species. To explore the molecular mechanisms of this critical process in a non-model organism, the tropical abalone Haliotis asinina, we emplo...
ORGANISM(S): Haliotis asinina 
2010-05-19 | E-GEOD-13039 | biostudies-arrayexpress
GenomicsDevelopment and Use of Network Infrastructure for High-Throughput GWA Studies

The "Development and Use of Network Infrastructure for High-Throughput GWA Studies" project is collaboration between Group Health Cooperative (GH), the University of Washington (UW), and the Fred Hutchinson Cancer Research Center (FHCRC). It is one of 5 sites participating in The Electronic Me...

phs000234.v1.p1 | EGA
UnknownCommon genetic variants influence human subcortical brain structures.
Not available
S-EPMC4393366 | biostudies-literature
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