The 4-6 minute fraction from the HPLC fractionation of the bacterial culture supernatant of porcine-derived probiotic Bacillus strain 541.

Gut microbiota modulation by a probiotic is a novel therapy for hypercholesterolemia mitigation. This study initially investigated the potential hypocholesterolemic effect of Bacillus sp. DU-106 in hypercholesterolemic rats and explored its potential relation with gut microbiota. Sprague-Dawley r...

Chinese yam tubers are nutrient-rich but highly susceptible to mechanical damage during harvest, which facilitates pathogenic fungal infection at wound sites. This study aimed to identify pathogenic fungi from postharvest yam wounds and screen native endophytic bacteria with antifungal activity f...

Phytophthora nicotianae is an oomycete pathogen of global significance threatening many important crops. It is mainly controlled by chemosynthetic fungicides, which endangers ecosystem and human health; thus, there is an urgent need to explore alternatives for these fungicides. In this s...

This study investigated the effects of Bacillus licheniformis supplementation on the gut metabolic profile of patients with mild-to-moderate active ulcerative colitis (UC). Patients received either mesalazine alone or mesalazine combined with Bacillus licheniformis. Fecal samples were collected a...

Ecologically derived synthetic communities can provide robust plant benefits, yet generalizable rules for assembling multifunctional consortia remain limited. We hypothesized that a “top-down” community assembled from an ecological core would yield complementary functions and resilience superior ...

This study evaluated the effects of dietary Bacillus coagulans supplementation on muscle nutritional quality and intestinal metabolomics in juvenile four-finger threadfin (Eleutheronema tetradactylum). A total of 420 healthy juveniles were randomly assigned to a control group or a B. coagulans su...

Small volatile molecules are considered to play a role in promoting plant growth, with acetoin and 2,3-butanediol being representative examples. In this study, we employed metabolic engineering of Bacillus subtilis to enhance the production of acetoin and 2,3-butanediol, and investigated the...