Sort   by:  
 Page size 
MetabolomicsSystematic identification of bacterial factors driving Staphylococcus aureus intracellular lifestyle in non-professional phagocytes

Staphylococcus aureus is a major human pathogen responsible for severe infections. While traditionally described as extracellular, increasing evidence establishes S. aureus as a facultative intracellular pathogen. Intracellularity contributes to immune evasion, dissemination, and antibiotic failu...

2025-10-26 | MTBLS13220 | MetaboLights
MetabolomicsOriginal data of bacterial antibiotic resistance lipidomics
Plasmid-mediated dissemination of mcr genes has severely compromised colistin efficacy, necessitating adjuvants that restore antibacterial potency without exacerbating toxicity. Despite their essential roles in bacterial survival and virulence, metal ion acquisition systems remain underexplored as t...
2026-08-13 | MTBLS15318 | MetaboLights
MetabolomicsMetabolic Rewiring of Bacterial Subpopulations Governs Polymyxin Responses in Acinetobacter baumannii
Polymyxins are often last-resort antibiotics against high-priority Gram-negative pathogens, particularly Acinetobacter baumannii. However, most mechanistic studies to date have overlooked the heterogeneity within bacterial populations during polymyxin treatment. Using time-lapse imaging and propidiu...
2026-07-27 | MTBLS14745 | MetaboLights
MetabolomicsModeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets
Not available
ORGANISM(S): Brugia malayi 
ST001258 | MetabolomicsWorkbench
MetabolomicsMetabolite detection and analysis of bacterial strains
This study investigated whether P. oxydans-secreted metabolites function as upstream metabolic signals that modulate host responses. We therefore compared the extracellular metabolomic profiles of P. oxydans cultured under control conditions and under 10% PEG 6000-induced osmotic stress.
2026-07-03 | MTBLS14926 | MetaboLights
MetabolomicsRapid Evaporative Ionisation Mass Spectrometry (REIMS) Provides Accurate Direct from Culture Species Identification within the Genus Candida
Members of the genus Candida, such as C. albicans and C. parapsilosis, are important human pathogens. Other members of this genus, previously believed to carry minimal disease risk, are increasingly recognised as important human pathogens, particularly because of variations in susceptibilities to wi...
2017-11-01 | MTBLS383 | MetaboLights
MetabolomicsBacterial extracellular vesicles as recyclable nutrient reservoirs

Bacterial extracellular vesicles (EVs) are known to mediate intercellular communication, virulence, and immune modulation. Here we show that bacteria can utilise EVs also as recyclable nutrient reservoirs. Using Bacillus cereus as a model organism, we demonstrate that EVs exhibit distin...

2026-02-18 | MTBLS13260 | MetaboLights
MetabolomicsDecoding the Human Gut Bacterial Plasmids in Colorectal Cancer
Gut plasmids show heightened sensitivity to gut microenvironmental changes compared to their bacterial hosts. To explore their significance in colorectal cancer (CRC), we analyzed metagenomic data from 863 participants (312 CRC, 387 high-risk, 164 low-risk). Plasmid and bacterial profiles were chara...
2026-04-26 | MTBLS14376 | MetaboLights
MetabolomicsDecoding the Human Gut Bacterial Plasmids in Colorectal Cancer
Gut plasmids show heightened sensitivity to gut microenvironmental changes compared to their bacterial hosts. To explore their significance in colorectal cancer (CRC), we analyzed metagenomic data from 863 participants (312 CRC, 387 high-risk, 164 low-risk). Plasmid and bacterial profiles were chara...
2026-04-24 | MTBLS14358 | MetaboLights
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (L-Alanine-treated macrophage metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7986 | MetaboLights
Sort   by:  
 Page size