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TranscriptomicsDefining the microglia transcriptome in multifunctional protein-2 deficient mice
Purpose: We purified whole brain microglia of MFP2 knockout mice and control mice utilizing percoll gradient and FACS sorting, followed by microarray analysis to define the molecular changes in MFP2 knockout mice at the endstage of the disease. We compared the microglia transcriptome of Mfp2-/- micr...
ORGANISM(S): Mus musculus 
2015-04-14 | E-GEOD-66420 | biostudies-arrayexpress
TranscriptomicsAMPK stimulation and PGC-1 alpha suppression in peroxisome deficient hepatocytes favor catabolic over anabolic carbohydrate metabolism
These arrays contain data from the livers of 10 week old L-Pex5 -/- male mice 6 arrays, 3 biological replicates
ORGANISM(S): Mus musculus 
2012-01-06 | E-GEOD-27720 | biostudies-arrayexpress
MetabolomicsPEROXISOMAL-MITOCHONDRIAL INTERPLAY ALTERATIONS IN SKELETAL MUSCLE RESULT IN EARLY-ONSET SARCOPENIA

Adjustments in muscle mass and metabolic demand are crucial for regulating whole-body metabolism, locomotion, eating, and respiration. Therefore, skeletal muscle is a central influencer of several human diseases. Muscle dysfunction correlates with the onset and progression of several metabolic di...

2025-09-15 | MTBLS12833 | MetaboLights
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