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TranscriptomicsGene expression profiling of HOS (human osteosarcoma) cells exposed to fluoride
Though fluoride is considered an essential trace element, chronic exposure to fluoride is known to cause toxic effects. Chronic exposure of high concentration of fluoride may leads to fluorosis. To understand the molecular mechanism of fluoride induced toxicity gene expression profiling was performe...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-70719 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of HepG2 cells exposed to Endosulfan
HepG2 cells grown in DMEM media were treated with 15M-BM-5M Endosulfan in prescence of S9-mix and total RNA was isolated from cells after 24 hour exposure Cells grown in 75mm2 flask. two replicates for control and two for treatment
ORGANISM(S): Homo sapiens 
2015-01-20 | E-GEOD-58257 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profile in HOS cells exposed to sodium fluoride
Fluorosis is caused due to excess of fluoride intake over a long period of time. Aberrant change in RUNX2-mediated signaling cascade is one of the decisive steps during the pathogenesis of fluorosis. Till date, role of fluoride on the epigenetic alterations is not studied. In the present study, glob...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-57550 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of SHSY5Y cells exposed to manganese
The trace element manganese is essential for normal development for all the organisms. Overexposure of manganese may leads to multiple neuronal disorders such as Parkinson, manganism. To explore the molecular mechanism of manganese induced neurotoxicity, gene expression profiling was performed on hu...
ORGANISM(S): Homo sapiens 
2016-07-01 | E-GEOD-70845 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of SHSY5Y cells exposed to Endosulfan
SHSY5Y cells grown in MEM:F12 media (1:1) were treated with Endosulfan and total RNA was isolated from cells after 24 hour exposure Three replicate were used for the experiment Cells grown in 75mm2 flask. three replicates for each sample
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-65140 | biostudies-arrayexpress
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