To identify the subproteome degraded by endosomal microautophagy (eMI) in a Bag6-dependent manner, we compared the proteome of late endosomal compartments LE/MVBs isolated from control(wild type) and Bag6(-) cells using SILAC labeling and quantitative proteomics.
Mice were infected with the pancreatic cancer cell line Pan02 (into their pancreas). 30 days later, pancreas was extracted, cells digested and BD Rhapsody RNAseq targeted against the MM immune panel was performed.
This experiment was performed to estimate the difference between DCs stimulated with intracellular ROS or LPS. Total RNA obtainded from DCs stimulated with intracellular ROS or LPS was analyzed for transcriptome
All non-essential protein kinases and phosphatases knockouts have been investigated by expression profiling. To investigate redundancy, double mutants are profiled that show a reduced growth according to synthetic genetic interaction data.
