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GenomicsGenome-wide binding sites of Progesterone receptor (PGR) isoforms PGR-A and PGR-B during differentiation of human endometrial stromal cells
We report the genome-wide binding sites of PGR-A and PGR-B at 2h of in vitro differentiation of human endometrial stromal cells that express either PGR-A or PGR-B. Progesterone, acting through the progesterone receptors (PGRs), is one of the most critical regulators of endometrial differentiation, k...
ORGANISM(S): Homo sapiens 
2015-04-27 | E-GEOD-62475 | biostudies-arrayexpress
TranscriptomicsExpression data of PGR isoforms, PRA and PRB, regulated genes in differentiating human endometrial stromal cells
gene expression at 6h of differentiation of Human endometrial stromal cell expressing either or both of PRA and PRB Endogenous PGR expression is silenced with siRNA mediated knockdown. Then, cells are transduced with adenovirus exressing flag tagged PRA or flag tagged PRB. Human endometrial stromal ...
ORGANISM(S): Homo sapiens 
2015-04-27 | E-GEOD-48853 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of uterine stromal cells isolated from Hand2 floxed and Hand2 ablated mice on day 4 of pregnancy
Our previous study revealed that the basic helix-loop-helix transcription factor Hand2 is a downstream target of progesterone signaling in mouse uterine stroma at the time of implantation. Further, conditional deletion of Hand2 in mouse uterus leads to implantation failure due to impaired uterine ep...
ORGANISM(S): Mus musculus 
2011-06-03 | E-GEOD-25881 | biostudies-arrayexpress
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