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Invasion of cancer cells into peripheral nerves, known as perineural invasion (PNI), is an established risk factor for cancer recurrence and metastasis. However, there are no approaches available to specifically target PNI-competent cancer cells for diagnostic and therapeutic purposes. The lack of i...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD059147 | Pride
Rare inherited diseases caused by mutations in the copper transporters SLC31A1 (CTR1) or ATP7A induce copper deficiency in the brain, causing seizures and neurodegeneration in infancy through poorly understood mechanisms. Here, we used multiple model systems to characterize the molecular mechanisms ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD059097 | Pride
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