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MetabolomicsELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease with distinct molecular subtypes described as classical/progenitor and basal-like/squamous PDAC. We hypothesized that integrative transcriptome and metabolome approaches can identify candidate genes whose inactivation contributes to ...
2024-04-02 | MTBLS9418 | MetaboLights
GenomicsDerivation of novel human ground state naM-CM-/ve pluripotent stem cells
Mouse embryonic stem (ES) cells are isolated from the inner cell mass of blastocysts, and can be preserved in vitro in a naive inner-cell-mass-like configuration by providing exogenous stimulation with leukaemia inhibitory factor (LIF) and small molecule inhibition of ERK1/ERK2 and GSK3b signalling ...
ORGANISM(S): Homo sapiens 
2013-11-28 | E-GEOD-52617 | biostudies-arrayexpress
TranscriptomicsDerivation of novel human ground state naM-CM-/ve pluripotent stem cells
Mouse embryonic stem (ES) cells are isolated from the inner cell mass of blastocysts, and can be preserved in vitro in a naive inner-cell-mass-like configuration by providing exogenous stimulation with leukaemia inhibitory factor (LIF) and small molecule inhibition of ERK1/ERK2 and GSK3b signalling ...
ORGANISM(S): Homo sapiens 
2013-10-29 | E-GEOD-46872 | biostudies-arrayexpress
UnknownPathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria.
Not available
S-EPMC4968715 | biostudies-literature
GenomicsDerivation of novel human ground state naM-CM-/ve pluripotent stem cells.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-11-29 | E-GEOD-52824 | biostudies-arrayexpress
GenomicsThe H3K27 demethylase Utx facilitates somatic and germ cell epigenetic reprogramming to pluripotency [ChIP-Seq]
Pluripotency can be induced in somatic cells by ectopic expression of defined transcription factors, however the identity of epigenetic regulators driving the progression of cellular reprogramming requires further investigation. Here we uncover a non-redundant role for the JmjC-domain-containing pro...
ORGANISM(S): Mus musculus 
2012-05-30 | E-GEOD-37821 | biostudies-arrayexpress
UnknownThe impact of a tailored nutrition intervention delivered for the duration of hospitalisation on daily energy delivery for patients with critical illness (INTENT): a phase II randomised controlled trial.
Not available
S-EPMC11706088 | biostudies-literature
UnknownClinical signs and symptoms in a joint model of four disease activity parameters in juvenile dermatomyositis: a prospective, longitudinal, multicenter cohort study.
Not available
S-EPMC6094880 | biostudies-literature
UnknownMuscle Biopsy Findings in Combination With Myositis-Specific Autoantibodies Aid Prediction of Outcomes in Juvenile Dermatomyositis.
Not available
S-EPMC5091622 | biostudies-literature
UnknownEfficacy and Safety of Cyclophosphamide Treatment in Severe Juvenile Dermatomyositis Shown by Marginal Structural Modeling.
Not available
S-EPMC5947636 | biostudies-literature
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