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UnknownControl of HIV-1 in elite suppressors despite ongoing replication and evolution in plasma virus.
Not available
S-EPMC2898225 | biostudies-literature
UnknownModelling bodyweight to avoid anthelmintic underdosing of goats in resources-limited settings.
Not available
S-EPMC9911490 | biostudies-literature
ProteomicsKinome profiling of osteosarcoma patient-derived xenograft TT2 treated with palbociclib
Osteosarcoma (OS) is the most common primary bone cancer in adolescents, young adults (AYA), and children, with up to 25% of patients developing metastatic disease, primarily in the lungs. Despite survival rates being >70% for localized tumors, patients with metastatic OS have <30% survival due to l...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD069093 | Pride
Kinase Inhibitor Bead Pi3k Cdk4/6 Mtor 
ProteomicsThermal proteome profilng of BMAL1 ligand CCM in U2OS cell lysate
The master transcription factor BMAL1-CLOCK is crucial for orchestrating rhythmic gene expression and governing circadian rhythms. Pharmacological manipulation of this central circadian regulator requires accessible protein cavities and selective compounds. By targeting BMAL1 through a resident cav...
ORGANISM(S): Homo sapiens (Human) 
2025-02-03 | PXD049298 | Pride
Thermal proteome profiling 
UnknownCMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans.
Not available
S-EPMC6070316 | biostudies-literature
TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
UnknownEnsuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks.
Not available
S-EPMC8630030 | biostudies-literature
UnknownNirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors.
Not available
S-EPMC11225596 | biostudies-literature
UnknownDNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution.
Not available
S-EPMC12425823 | biostudies-literature
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