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UnknownSkilled Movements Require Non-apoptotic Bax/Bak Pathway-Mediated Corticospinal Circuit Reorganization.
Not available
S-EPMC5510485 | biostudies-literature
UnknownLapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation.
Not available
S-EPMC2574656 | biostudies-literature
ProteomicsPharmacological inhibition of mitochondrial soluble adenylyl cyclase in astrocytes causes activation of AMP-activated protein kinase and induces breakdown of glycogen
Astrocytes contain the majority of the brain’s supply of glycogen which has been suggested to play an important role in neuronal synaptic plasticity. This may be mediated by release of glycogen-derived lactate or glutamine supporting neuronal metabolism or via induction of neuronal signaling pathway...
ORGANISM(S): Mus musculus (Mouse) Acyrthosiphon pisum (Pea aphid) 
2021-08-13 | PXD027901 | Pride
Mouse astrocytes Amp-activated protein kinase Energy metabolism Adenylyl cyclase Phosphorylation 
Transcriptomicsbak1 bkk1 flg22 - Flagellin response in mpk mutants
au-09-01_mpk_flagellin_edu - bak1 bkk1 flg22 - Investigate flagellin mpk dependent genes. - 2 weeks Bak1bkk1 plants treated with flg22 1h 1 microM 2 dye-swap - CATMA arrays
ORGANISM(S): Arabidopsis thaliana 
2012-01-01 | E-GEOD-23184 | biostudies-arrayexpress
TranscriptomicsLong non-coding RNA HOTAIR is an independent prognostic marker of metastasis in estrogen receptor positive primary breast cancer
Expression of HOX transcript antisense intergenic RNA (HOTAIR)—a long intergenic non-coding RNA (lincRNA)—has been examined in a variety of human cancers, and overexpression of HOTAIR is correlated with poor survival among breast, colon, and liver cancer patients. In this retrospective study, we exa...
ORGANISM(S): Homo sapiens 
2013-11-29 | E-GEOD-48408 | biostudies-arrayexpress
UnknownAerobic endurance training versus relaxation training in patients with migraine (ARMIG): study protocol for a randomized controlled trial.
Not available
S-EPMC3492021 | biostudies-literature
TranscriptomicsClassifications within Molecular Subtypes Enables Identification of BRCA1/BRCA2 Mutation Carriers by RNA Tumor Profiling
Pathogenic germline mutations in BRCA1 or BRCA2 are detected in less than one third of families with a strong history of breast cancer. It is therefore expected that mutations still remain undetected by currently used screening methods. In addition, a growing number of BRCA1/2 sequence variants of u...
ORGANISM(S): Homo sapiens 
2013-06-28 | E-GEOD-40115 | biostudies-arrayexpress
UnknownTRAIL signaling promotes entosis in colorectal cancer.
Not available
S-EPMC8563286 | biostudies-literature
ProteomicsA jack of all trades and a master of some: remodeling of signaling pathways downstream of CFIm 3’ end processing factor
The mammalian cleavage factor I (CFIm) has been implicated in alternative polyadenylation (APA) in a broad range of contexts, from cancers to learning deficits and parasite infections. To uncover the molecular pathways that translate CFIm expression levels into these observed phenotypes, we carried ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-11 | PXD027034 | Pride
Tmt Phosphorylation Cfim3 
UnknownMitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Not available
S-EPMC9640553 | biostudies-literature
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