Sort   by:  
 Page size 
MetabolomicsSPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids
Characterization of endogenous metabolites and xenobiotics is essential to deconvoluting the genetic and environmental causes of disease. However, surveillance of chemical exposure and disease-related changes in large cohorts requires an analytical platform that offers rapid measurement, high sensit...
2017-02-14 | MTBLS427 | MetaboLights
ProteomicsMulti-Omic Evidence of Brain Region Specific APOE Genotype Perturbations in Alzheimer's Disease
Simultaneous extraction of proteins and lipids from human frontal cortex and cerebellum brain tissue was performed using the MPLEx procedure for both control and Alzheimer's disease patients. The isolated proteins were then reduced, alkylated, tryptically digested and evaluated with LC-IMS-MS. The p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-08 | MSV000092627 | MassIVE
MetabolomicsGNPS - Multi-Omic Evidence of Brain Region Specific APOE Genotype Perturbations in Alzheimer's Disease
Simultaneous extraction of proteins and lipids from human frontal cortex and cerebellum brain tissue was performed using the MPLEx procedure for both control and Alzheimer's disease patients. The isolated proteins were then reduced, alkylated, tryptically digested and evaluated with LC-IMS-MS. The p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-08 | MSV000092627 | GNPS
GenomicsMsn2-mediated nucleosome remodeling dynamics
The aim of this experiment was to determine, using MNAse-Seq, how nucleosomes get remodeled during an Msn2 activation timecourse genome-wide. Diploid strain EY2807/ASH79 with genotype TPK1M164G TPK2M147G TPK3M165G msn4::TRP1/LEU2 MSN2-mCherry NHP6a-iRFP::kanMX was used. This strain is PKAas, so upon...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-12 | E-MTAB-1950 | biostudies-arrayexpress
ProteomicsMolecular Signatures of Preeclampsia and Gestational Diabetes Mellitus Utilizing Multi-Omics Analyses, Part 2
The application of multi-omic evaluations, multi-dimensional analysis methods, and new cheminformatics-based visualization tools to provide an in depth understanding of the molecular changes taking place in preeclampsia (PRE) and gestational diabetes mellitus (GDM) patients. Since PRE and GDM are tw...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-02 | MSV000085361 | MassIVE
ProteomicsMolecular Signatures of Preeclampsia and Gestational Diabetes Mellitus Utilizing Multi-Omics Analyses, Part 1
The application of multi-omic evaluations, multi-dimensional analysis methods, and new cheminformatics-based visualization tools to provide an in depth understanding of the molecular changes taking place in preeclampsia (PRE) and gestational diabetes mellitus (GDM) patients. Since PRE and GDM are tw...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-01 | MSV000085357 | MassIVE
MetabolomicsGNPS - Molecular Signatures of Preeclampsia and Gestational Diabetes Mellitus Utilizing Multi-Omics Analyses, Part 1
The application of multi-omic evaluations, multi-dimensional analysis methods, and new cheminformatics-based visualization tools to provide an in depth understanding of the molecular changes taking place in preeclampsia (PRE) and gestational diabetes mellitus (GDM) patients. Since PRE and GDM are tw...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-01 | MSV000085357 | GNPS
ProteomicsFrom plants to ants: Evaluating lipidomic changes in leaf-cutter ant fungus gardens
Leaf-cutter ants use fresh plant material to cultivate an obligate mutualistic fungus Leucoagaricus gongylophorus in specialized fungus gardens to access and transform nutrients from plant biomass that would otherwise be unavailable to the ants. Here, we evaluated the lipidomic differences between t...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2019-10-30 | MSV000084520 | MassIVE
TranscriptomicsRedefining the translational status of 80S monosomes
Fully assembled ribosomes exist in two populations: polysomes and monosomes. While the former has been studied extensively, to what extent translation occurs on monosomes and its importance for overall translational output remains controversial. Here, we used ribosome profiling to examine the transl...
ORGANISM(S): Saccharomyces cerevisiae 
2016-02-11 | E-GEOD-76117 | biostudies-arrayexpress
TranscriptomicsPhosphate metabolism in Saccharomyces cerevisiae
Investigation of Saccharomyces cerevisiae phosphate metabolism. Cells starved for phosphate, cells grown with intermediate and high phosphate concentrations, and PHO4 mutant cells examined.
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-05 | E-GEOD-603 | biostudies-arrayexpress
Sort   by:  
 Page size