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TranscriptomicsA gp130-induced Src/Yes-YAP Cascade Links Inflammation to Regeneration in the Mammalian Intestine
gp130Act cDNA was PCR-amplified and inserted into a plasmid containing the 12.4-kb Villin promoter. The 15.7-kb expression cassette was excised by PmeI digestion, purified, and injected into fertilized C57BL/6 oocytes to obtain founder mice, two of which transmitted the gp130Act transgene. Small int...
ORGANISM(S): Mus musculus 
2015-02-21 | E-MTAB-2400 | biostudies-arrayexpress
UnknownNorth Carolina physician-based preventive oral health services improve access and use among young Medicaid enrollees.
Not available
S-EPMC4331078 | biostudies-literature
TranscriptomicsKey Role of MicroRNA in the Regulation of Granulocyte Macrophage Colony-stimulating Factor Expression in Murine Alveolar Epithelial Cells (AEC) during Oxidative Stress
A genome wide microarray identified 19 candidate miRNA altered in primary AEC during oxidative stress with reversal by treatment with GM-CSF. Three of these microRNA (miR 133a, miR133a* and miR133b) are also predicited to bind the GM-CSF 3 UTR. 4 samples. Primary murine alveolar epithelial cells wer...
ORGANISM(S): Mus musculus 
2014-04-11 | E-GEOD-56687 | biostudies-arrayexpress
UnknownThe Role of Nurses and Midwives in Expanding and Sustaining Voluntary Medical Male Circumcision Services for HIV Prevention: A Systematic and Policy Review.
Not available
S-EPMC9295017 | biostudies-literature
GenomicsThe Ovarian Cancer Association Consortium Data Access Committee
Data Access Committee EGAC00001000616
EGAC00001000616 | EGA
TranscriptomicsExpression data from the partially synthetic yeasts SynIXR-1D, -6B, -22D, and controls.
We have replaced the right arm of chromosome IX in Saccharomyces cerevisiae with a synthetic version to generate synIXR haploids. The synthetic chromosome features multiple sequeunce modifications. We analyzed gene expression by microarray analysis in three synIXR haploids (1D, 6B, and 22D) to dete...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-13 | E-GEOD-31326 | biostudies-arrayexpress
TranscriptomicseQTL Mapping of the Yeast Ethanol Response
In a previous study, we identified extensive natural variation in the response to acute ethanol treatment in three yeast strains: a lab strain derived from the commonly used S288c (DBY8268), vineyard isolate M22, and oak soil strain YPS163. Many expression differences persisted across several module...
ORGANISM(S): Saccharomyces cerevisiae 
2014-10-02 | E-GEOD-54196 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomic analysis between a high and a low sulfite producers wine yeast strains
The goal of this study was to compare the expression level of the whole genome of two wine yeast strains highly differing in their sulfite production (High producer strain: 10281A; Low producer strain: 1764A). Conditions maximizing SO2 production were selected: nitrogen rich media (425 mg/l assimila...
ORGANISM(S): Saccharomyces cerevisiae 
2015-05-14 | E-GEOD-55083 | biostudies-arrayexpress
TranscriptomicsA Myc transcriptional program that is independent of EMT drives a poor prognosis tumor-propagating phenotype in HER2+ breast cancer
The HER2 (ERBB2) and MYC genes are commonly amplified genes in breast cancer, yet little is known about their molecular and clinical interaction. Using a novel chimeric mammary transgenic approach and in vitro models, we demonstrate markedly increased self renewal and tumour propagating capability o...
ORGANISM(S): Homo sapiens 
2013-09-24 | E-GEOD-43730 | biostudies-arrayexpress
GenomicsGenome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing

In this study, we whole genome sequenced tumor/normal pairs from three pancreatic adenocarcinoma patients to separately characterize each patient with respect to somatic alterations. For 2 patients for whom tumor RNA was available, we also performed RNA sequencing to evaluate gene expression chan...

phs000550.v1.p1 | EGA
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