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GenomicsRetrotransposon-based profiling of mammalian epigenomes: DNA methylation of IAP LTRs in embryonic stem, somatic and cancer cells
In this study, we analyzed the DNA methylation levels of 4799 IAP LTRs in three murine cell types: AB2.2 ES cells, somatic cells and a neuroblastoma cell line Neuro2A. According to the results, half of the IAP LTR retrotransposons show constant methylation patterns between the three cell types where...
ORGANISM(S): Mus musculus 
2015-06-15 | E-GEOD-60007 | biostudies-arrayexpress
GenomicsDNA methylation variation of human-specific Alu repeats
DNA methylation is the major repression mechanism for human retrotransposons, such as the Alu family. Here, we have derived methylation levels regarding 5238 loci belonging to two Alu subfamilies, AluYa5 and AluYb8, using High-Throughput Targeted Repeat Element Bisulfite Sequencing (HT-TREBS). ...
ORGANISM(S): Homo sapiens 
2016-10-27 | E-GEOD-74420 | biostudies-arrayexpress
TranscriptomicsPeg3 mutational effects on reproduction and placenta-specific gene families
Peg3 (paternally expressed gene 3) is an imprinted gene encoding a DNA-binding protein. This gene plays important roles in controlling fetal growth rates and nurturing behaviors. In the current study, a new mutant mouse model has been generated to further characterize the functions of this DNA-bin...
ORGANISM(S): Mus musculus 
2014-09-11 | E-GEOD-50818 | biostudies-arrayexpress
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