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MetabolomicsGlobal Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
The interplay between the Apicomplexan parasite Toxoplasma gondii and its host has been largely studied. However, molecular changes at the metabolic level in the host central nervous system and pathogenesis-associated metabolites during brain infection are largely unexplored. We used a global metabo...
2017-01-27 | MTBLS217 | MetaboLights
MetabolomicsSulfadiazine Sodium Improves Dysfunctional Metabolomics in Toxoplasma gondii-infected Mice
Toxoplasma gondii is an obligate intracellular protozoan parasite that poses a severe threat to human health, especially those immune-compromised individuals. Sulfadiazine sodium (SDZ) is widely used for the treatment of human toxoplasmosis. However, systems biology researches on the therapeutic eff...
2019-06-18 | MTBLS852 | MetaboLights
MetabolomicsMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
GenomicsMus musculus strain:balbc
Mus musculus strain:balbc Raw sequence reads
PRJNA1285315 | ENA
UnknownCD3Ɛ immune restorative ability induced by Maitake Pro4x in immunosupressed BALBc mice.
Not available
S-EPMC9502923 | biostudies-literature
TranscriptomicsTranscription profiling of mouse ark adapted and light damaged BALBc (albino) retinal pigmented epithelium
Transcriptional profiles were compared between dark adapted and light damaged BALBc (albino) mouse RPE. Experiment Overall Design: BALBc mice were dark adapted for one week. To produce light damage a subset of the mice were then exposed to 6,000 lux white fluorescent light for 1.5 hours. RPEs were c...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-13074 | biostudies-arrayexpress
GenomicsSingle-cell transcriptional profiles of BM, PB and lung neutrophils from naïve (BALBc/J) and 4T1 tumor-bearing mice
Single-cell transcriptional profiles of BM, PB and lung neutrophils from naïve (BALBc/J) and 4T1 tumor-bearing mice
PRJNA897000 | ENA
TranscriptomicsPhloridzin reduces blood glucose levels and alters hepatic gene expression in normal BALB/c mice
We previously showed that a diet containing phloridzin suppressed the blood glucose levels in streptozotocin-induced diabetic mice most likely by inhibiting glucose absorption from the small intestine. In this study, we showed that 0.5% and 1% phloridzin diets significantly reduce the blood glucose ...
ORGANISM(S): Mus musculus 
2012-05-17 | E-GEOD-37415 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse BALBc strain mesenteric lymph nodes after response to common allergens.
In this study, MLN transcriptome profiling of female BALB/c mice was conducted in order to explore the molecular mechanism(s) of antigen sensitization using three of the most common food allergens; BLG, OVA and PNA. Analysis of cDNA microarray data revealed a complex network of genes that is modulat...
ORGANISM(S): Mus musculus 
2011-05-11 | E-MEXP-2676 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse BALBc albino retinas compared BETWEEN dark adapted AND light damaged animals
Transcriptional profiles were compared between dark adapted and light damaged BALBc (albino) mouse retinas. Experiment Overall Design: BALBc mice were dark adapted for one week. To produce light damage a subset of the mice were then exposed to 6,000 lux white fluorescent light for 6 hours. Retinas ...
ORGANISM(S): Mus musculus 
2008-04-07 | E-GEOD-10528 | biostudies-arrayexpress
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