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UnknownStand up to cancer phase Ib study of pan-phosphoinositide-3-kinase inhibitor buparlisib with letrozole in estrogen receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer.
Not available
S-EPMC3986383 | biostudies-literature
TranscriptomicsGene expression profiling of MDA231, BT549, and SUM159PT cells after selumetinib treatment or DUSP4 siRNA knockdown
MDA231, BT549, and SUM159PT basal-like breast cancer cell lines were transfected with non-targeting siRNA (siCONTROL), siRNA targeting DUSP4 (siDUSP4), or siCONTROL + 4 or 24 hr of 1uM selumetinib. Cells were harvested at 96 hr post-siRNA transfection. Data were Log2 RMA normalized. We sought to i...
ORGANISM(S): Homo sapiens 
2013-09-03 | E-GEOD-41816 | biostudies-arrayexpress
TranscriptomicsControlled ErbB receptor dimerization
In order to better understand signaling events following receptor dimerization involving HER2, we have generated an experimental system in which ErbB dimerization can be controlled. We used gene expression microarrays to identify genes and pathways that are differentially activated by HER2 homodimer...
ORGANISM(S): Homo sapiens 
2011-05-13 | E-GEOD-22288 | biostudies-arrayexpress
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