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TranscriptomicsHigh-time-resolution dynamic analysis of human regulatory T cell (Treg) / CD4+ T-effector cell (Teff) activation
Human FOXP3+CD25+CD4+ regulatory T cells (Tregs) play a dominant role in the maintenance of immune homeostasis. Several genes are known to be important for murine Tregs, but for human Tregs the genes and underlying molecular networks controlling the suppressor function still largely remain unclear. ...
ORGANISM(S): Homo sapiens 
2012-11-23 | E-GEOD-11292 | biostudies-arrayexpress
TranscriptomicsEarly-induced genes of human regulatory CD4+CD25hi Treg and CD4+CD25- Th cells
Goals and objectives of this study: to identify genes preferentially induced in human CD4+CD25hi Treg cells following T-cell activation with potential role for stabililization & maintenance of the regulatory program. Keywords: T-cell receptor stimulation, gene-regulation, comparative gene expressio...
ORGANISM(S): Homo sapiens 
2009-04-20 | E-GEOD-13017 | biostudies-arrayexpress
TranscriptomicsHuman activated Treg cells and retrovirally engineered Th cells, transduced with GARP, FOXP3 or control GFP vector
Goals and objectives of this study: to identify genes of the Treg signature induced by consitutive expression of GARP or FOXP3 in antigen-specific Th cells with potential role for stabililization & maintenance of the regulatory program. Keywords: T-cell receptor stimulation, gene-regulation, compar...
ORGANISM(S): Homo sapiens 
2009-04-20 | E-GEOD-13234 | biostudies-arrayexpress
UnknownEmbryonic development of selectively vulnerable neurons in Parkinson's disease.
Not available
S-EPMC5484687 | biostudies-literature
UnknownHospitalization prediction from the emergency department using computer vision AI with short patient video clips.
Not available
S-EPMC11659512 | biostudies-literature
UnknownA novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51.
Not available
S-EPMC4703882 | biostudies-literature
UnknownA roadmap towards personalized immunology.
Not available
S-EPMC5802799 | biostudies-literature
TranscriptomicsThe study of inflammatory responses in mammalian macrophages with LPS stimulation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-02-24 | E-GEOD-76563 | biostudies-arrayexpress
UnknownMIC-MAC: An automated pipeline for high-throughput characterization and classification of three-dimensional microglia morphologies in mouse and human postmortem brain samples.
Not available
S-EPMC6617786 | biostudies-literature
TranscriptomicsLPS stimulation of human PBMC-derived macrophages
Immunoresponsive gene 1 (IRG1) is one of the highest induced genes in macrophages under pro-inflammatory conditions and its function has been recently described: it codes for immune-responsive gene 1 protein/cis-aconitic acid decarboxylase (IRG1/CAD), an enzyme catalyzing the production of itaconic ...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-76561 | biostudies-arrayexpress
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