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Transcriptomics
(1)
Organisms
Homo sapiens
(1)
Repository
biostudies-arrayexpress
(1)
Publication Date
2020
(1)
Study type
Transcription profiling by array
(1)
Release Date
2020
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Dual-mechanism ERK1/2 inhibitors exploit a distinct binding mode to block phosphorylation and nuclear accumulation of ERK1/2, resulting in enhanced potency
Here we have characterized the MoA of Erk inhibitors in terms of Erk1/2 signalling, gene expression and antiproliferative efficacy in BRAF and RAS mutant cell lines.
ORGANISM(S):
Homo sapiens
2020-10-08
|
E-MTAB-7959
|
biostudies-arrayexpress
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