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UnknownHumanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
Not available
S-EPMC5892726 | biostudies-literature
TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (e...
ORGANISM(S): Mus musculus 
2012-06-21 | GSE36284 | GEO
TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-36284 | biostudies-arrayexpress
TranscriptomicsDendritic Cells
Dendritic cells (DC) play a crucial role in initiating, shaping and controlling the immune response. They are the most important antigen presenting cells in the immune system. DC can be divided in immature and mature DC. DCs reside in an immature state in most tissues or they circulate in the blood,...
ORGANISM(S): Homo sapiens 
2010-01-01 | GSE15956 | GEO
UnknownDendritic-cell-based therapeutic cancer vaccines.
Not available
S-EPMC3788678 | biostudies-literature
TranscriptomicsLongitudinal clonal IgG cross-reactivity profiles of coronavirus-specific B-cells in COVID-19 patients
We investigated the kinetics, breadth, magnitude, and level of cross-reactivity of IgG antibodies against SARS-CoV-2 and heterologous seasonal (HCoV-NL63, -229E, -OC43 and -HKU1) and epidemic coronaviruses (SARS-CoV, hCoV-MERS) at the clonal level in patients with mild or severe COVID-19 as well as ...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-12161 | biostudies-arrayexpress
TranscriptomicsDendritic Cells
Dendritic cells (DC) play a crucial role in initiating, shaping and controlling the immune response. They are the most important antigen presenting cells in the immune system. DC can be divided in immature and mature DC. DCs reside in an immature state in most tissues or they circulate in the blood,...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-GEOD-15956 | biostudies-arrayexpress
UnknownInfluenza vaccines differentially regulate the interferon response in human dendritic cell subsets.
Not available
S-EPMC5484150 | biostudies-literature
TranscriptomicsFine-tuning of human dendritic cells regulation revealed by translational profiling
Dendritic cells (DCs) are the sentinels of the mammalian immune system and they undergo a complex maturation process mediated by activation upon pathogen detection. Recent studies described the analysis of activated DCs by transcriptional profiling, but translation regulation was never taken in acco...
ORGANISM(S): Homo sapiens 
2009-12-30 | E-GEOD-14000 | biostudies-arrayexpress
UnknownHuman tonsil B-cell lymphoma 6 (BCL6)-expressing CD4+ T-cell subset specialized for B-cell help outside germinal centers.
Not available
S-EPMC3158181 | biostudies-literature
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