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TranscriptomicsCGH analysis of Candida albicans strains after in vitro evolution in the presence or absence of Fluconazole
Here we provide, for the first time, a longitudinal study of the prevalence, dynamics, and fixation of gross chromosomal rearrangements, including aneuploidy, in the presence and absence of fluconazole during a well-controlled in vitro evolution experiment. While no aneuploidy was detected in any o...
ORGANISM(S): Candida albicans 
2010-06-24 | E-GEOD-16423 | biostudies-arrayexpress
ModelsTwycross2010_Auxin_Transport
This is a model with 20 cells - 20 cytplasms and 21 apoplasts - as described in the article: Stochastic and deterministic multiscale models for systems biology: an auxin-transport case study. by Twycross J, Band LR, Bennett MJ, King JR, Krasnogor N. BMC Syst Bio...
2005-01-01 | MODEL1005200000 | BioModels
TranscriptomicsTestosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice
Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin (KISS1) do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have yet to be explored by genome-wide methods. Using micro-disse...
ORGANISM(S): Mus musculus 
2011-08-21 | E-GEOD-28383 | biostudies-arrayexpress
TranscriptomicsMessenger RNA is a functional component of a chromatin insulator complex
Chromatin insulators are DNA-protein complexes situated throughout the genome capable of demarcating independent transcriptional domains. Previous studies point to an important role for RNA in gypsy chromatin insulator function in Drosophila; however, the identity of these putative insulator-associa...
ORGANISM(S): Drosophila melanogaster 
2013-08-06 | E-GEOD-29991 | biostudies-arrayexpress
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