Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
To provide a more comprehensive analysis of the effects of OSD1 overexpression, we analyzed transcriptional profiles of Ws, bon1-2, osd1-4, and bon1-2 osd1-4 (all in Ws) by RNA-Seq technology.
Background Information: Primary open-angle glaucoma (POAG) is an age-related, intraocular pressure (IOP)-dependent progressive optic neuropathy that ultimately leads to irreversible blindness. Vision loss from POAG is a condition of public health significance. Current evidence suggests tha...
