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TranscriptomicsMicroarray of formalin-fixed, paraffin-embedded uninvolved terminal ileal tissue obtained from ileo-colic resection surgeries of Crohn’s disease and control patients
The interpretation of transcriptional profiling studies of intestinal tissue from Crohn’s disease patients and control patients can be confounded by differing proportions of cell subsets (e.g. immune cells) present in these samples. In this study, we aimed to control for cellular composition using s...
ORGANISM(S): Homo sapiens 
2018-05-22 | E-MTAB-5790 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling by Illumina sequencing technology
miRNAs are 19-25 nucleotides long small RNAs now well-known for their regulatory roles in the development and diseases through post-transcriptional and translational controls in a wide range of species. Mammalian hibernation is a physiological process involving dramatic metabolic suppression and cel...
ORGANISM(S): Urocitellus parryii 
2010-11-30 | E-GEOD-19807 | biostudies-arrayexpress
TranscriptomicsAnterior Heart Field (AHF)-conditional Mef2c Knockout
We have performed conditional inactivation of mef2c in the anterior heart field (AHF) of mice and observed a phenotypic spectrum of outflow tract anomalies in the conditional mutant hearts. In an effort to identify misregulated genes in the outflow tracts of the mutants, we have performed RNA-Seq o...
ORGANISM(S): Mus musculus 
2016-04-05 | E-GEOD-68147 | biostudies-arrayexpress
TranscriptomicsRNA-seq of formalin-fixed, paraffin-embedded uninvolved terminal ileal tissue obtained from ileo-colic resection surgeries of Crohns disease and control patients
The interpretation of transcriptional profiling studies of intestinal tissue from Crohns disease patients and control patients can be confounded by differing proportions of cell subsets (e.g. immune cells) present in these samples. In this study, we aimed to control for cellular composition using st...
ORGANISM(S): Homo sapiens 
2018-05-22 | E-MTAB-5783 | biostudies-arrayexpress
TranscriptomicsAnalysis of molecular signatures in mammalian hibernation
Mammalian hibernators display phenotypes similar to physiological conditions in non-hibernating species under conditions of calorie restriction and fasting, hypoxia, hypothermia, ischemia-reperfusion, and sleep. However, whether or how similarities are also reflected on molecular and genetic levels ...
ORGANISM(S): Urocitellus parryii 
2012-09-01 | E-GEOD-38700 | biostudies-arrayexpress
TranscriptomicsPreservation of bone mass and structure in hibernating black bears (Ursus americanus) through elevated expression of anabolic genes
Physical inactivity reduces mechanical load on the skeleton, which leads to losses of bone mass and strength in non hibernating mammalian species. Although bears are largely inactive during hibernation, they show no loss in bone mass and strength. To obtain insight into molecular mechanisms preventi...
ORGANISM(S): Ursus americanus 
2012-02-15 | E-GEOD-35796 | biostudies-arrayexpress
UnknownGenetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Not available
S-EPMC6463297 | biostudies-literature
UnknownEffects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT.
Not available
S-EPMC11873788 | biostudies-literature
UnknownDeath following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.
Not available
S-EPMC10364875 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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