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ProteomicsThe B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM
This data set contains the mass spectrometry raw files for the paper The B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM. In multiple sclerosis (MS) intrathecal B lymphocytes are directly involved in inflammation and secrete oligoclonal immunoglobulin. Ho...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-02-11 | MSV000086842 | MassIVE
UnknownTargeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses.
Not available
S-EPMC2515117 | biostudies-literature
TranscriptomicsComparative gene expression profiling of the EBV-positive NPC cell line C666.1 and normal primary tonsillar epithelial cells
In this study, we have performed comparative gene expression profiling of primary tonsil epithelial cells with the EBV-positive NPC cell line C666.1 using a human gene array. Differences in cellular gene expression was compared using RNA isolated from C666-1 cells and primary tonsil epithelial cells...
ORGANISM(S): Homo sapiens 
2013-09-06 | E-GEOD-39826 | biostudies-arrayexpress
TranscriptomicsWhole genome expression data comparison between WT and Cebpg-/- MEFs.
C/EBPβ is an important regulator of oncogene-induced senescence (OIS). Here we show that C/EBPγ, a heterodimeric partner of C/EBPβ whose biological functions are not well understood, inhibits cellular senescence. Cebpg-/- MEFs proliferated poorly, entered senescence prematurely, and expressed a p...
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-47777 | biostudies-arrayexpress
UnknownPatients with Epstein Barr virus-positive lymphomas have decreased CD4(+) T-cell responses to the viral nuclear antigen 1.
Not available
S-EPMC2605183 | biostudies-literature
UnknownTonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma.
Not available
S-EPMC2233668 | biostudies-literature
TranscriptomicsInfluence of C/EBPβ 3'UTR on RasV12 induced gene expression
C/EBPb is an auto-repressed protein that becomes posttranslationally activated by Ras-MEK-ERK signalling. C/EBPb is required for oncogene-induced senescence (OIS) of primary fibroblasts, but also displays pro-oncogenic functions in many tumour cells. Here, we show that C/EBPb activation by H-RasV12 ...
ORGANISM(S): Mus musculus 
2011-07-22 | E-GEOD-30834 | biostudies-arrayexpress
UnknownPhase II Intergroup Trial of Alisertib in Relapsed and Refractory Peripheral T-Cell Lymphoma and Transformed Mycosis Fungoides: SWOG 1108.
Not available
S-EPMC4500834 | biostudies-literature
TranscriptomicsComparison of Expression Profiles for Agrobacterium tumefaciens visR mutant to wild-type strain.
Many bacteria colonize surfaces and transition to a sessile mode of growth. The plant pathogen Agrobacterium tumefaciens produces a unipolar polysaccharide (UPP) adhesin at single cell poles that contact surfaces. Here we report that elevated levels of the intracellular signal cyclic diguanosine mon...
ORGANISM(S): Agrobacterium tumefaciens 
2014-08-21 | E-GEOD-60565 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lamb muscle from animals with maternal callipyge allele
Lambs that inherit a callipyge allele from their dam have an up-regulation of maternally imprinted transcripts near the callipyge mutation but do not exhibit muscle hypertrophy. It is not clear what effects these maternally expressed transcripts have in the muscle or how the inheritance of a materna...
ORGANISM(S): Ovis aries 
2009-06-22 | E-GEOD-11780 | biostudies-arrayexpress
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