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TranscriptomicsBG3 WT Repliseq
modENCODE_submission_5528 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The relative time of replication for all unique sequences in the Drosophila genome was determined by sequencing replicati...
ORGANISM(S): Drosophila melanogaster 
2012-10-04 | E-GEOD-41351 | biostudies-arrayexpress
TranscriptomicsS2 WT Repliseq
modENCODE_submission_5527 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The relative time of replication for all unique sequences in the Drosophila genome was determined by sequencing replicati...
ORGANISM(S): Drosophila melanogaster 
2012-10-04 | E-GEOD-41350 | biostudies-arrayexpress
TranscriptomicsKC WT Repliseq
modENCODE_submission_5526 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The relative time of replication for all unique sequences in the Drosophila genome was determined by sequencing replicati...
ORGANISM(S): Drosophila melanogaster 
2012-10-04 | E-GEOD-41349 | biostudies-arrayexpress
TranscriptomicsComparison of Cancer-Associated Genetic Abnormalities in Columnar-Lined Esophagus with and without Goblet Cells
The requirement of goblet cells (intestinal metaplasia; IM) to define BarrettM-bM-^@M-^Ys esophagus (BE) remains controversial as some studies have shown that the risk of progression to esophageal adenocarcinoma (EAC) is similar for non-goblet cell metaplasia (NGM) and IM. IM harbors genomic aberrat...
ORGANISM(S): Homo sapiens 
2012-12-15 | E-GEOD-40769 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
TranscriptomicsInsect larvae fed on resistant Zea mays (corn) expressing maize insect resistant 1 cysteine protease (Mir1-CP) compensate for Mir1-CP degradation of their peritrophic membrane by altering expression of midgut transcripts as revealed through mRNA-seq
Native host plant insect resistance in the maize inbred line Mp708 was developed by traditional plant breeding. Resistant Mp708 thwarts feeding by fall armyworm (Spodoptera frugiperda [J.E. Smith]; Lepidoptera: Noctuidae), numerous other lepidopteran pests, and the coleopteran western corn rootworm...
ORGANISM(S): Spodoptera frugiperda 
2012-12-01 | E-GEOD-42659 | biostudies-arrayexpress
TranscriptomicsKc WT Repliseq
modENCODE_submission_3630 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The relative time of replication for all unique sequences in the Drosophila genome was determined by sequencing replicati...
ORGANISM(S): Drosophila melanogaster 
2012-06-14 | E-GEOD-38709 | biostudies-arrayexpress
GenomicsCNV CME W1 Cl.8+ Cells
modENCODE_submission_3201 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Analysis of copy number variation across modENCODE Drosophila cell line by high throughput sequencing. We observe numero...
ORGANISM(S): Drosophila melanogaster 
2011-03-23 | E-GEOD-28136 | biostudies-arrayexpress
TranscriptomicsTranslation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3M-bM-^@M-^Y UTRs
The RNA helicase UPF1 is best known for its key function in mRNA nonsense-mediated mRNA decay (NMD), but has also been implicated in additional mRNA turnover mechanisms, telomere homeostasis, and DNA replication. In NMD, UPF1 recruitment to target mRNAs is thought to occur through interaction with r...
ORGANISM(S): Homo sapiens 
2013-06-20 | E-GEOD-47976 | biostudies-arrayexpress
GenomicsCNV S2-DRSC Cells
modENCODE_submission_2551 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Analysis of copy number variation across modENCODE Drosophila cell line by high throughput sequencing. We observe numero...
ORGANISM(S): Drosophila melanogaster 
2010-01-21 | E-GEOD-19956 | biostudies-arrayexpress
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