Sort   by:  
 Page size 
MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
ProteomicsProteomics of poly(ADP-ribosyl)ation uncovers a role for HIRA in the chromatin adaptation at ALT telomeres
The synthesis of poly(ADP-ribose) (PAR) reconfigures the local environment and recruits repair complexes to damaged chromatin. The degradation of PAR by PARG is essential for progression and completion of DNA repair. Here, we show that inhibition of PARG disrupts homology-directed repair (HDR) mech...
ORGANISM(S): Homo sapiens (Human) 
2020-10-12 | PXD020243 | Pride
Parps Cancer Histone Chromatin Telomere 
GenomicsConjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study
This data comes from a genome-wide association study in 1090 cases of scarring trachoma and 1531 controls from a non-selected multi-ethnic sampling of The Gambia. The data constitutes hard base calls at 1457295 features from the HumanOmni2.5-8 (Omni2.5) BeadChip. Three genotype-calling algorithms we...
EGAS00001001516 | EGA
GenomicsCAD - samples
WTCCC2 samples from Coronary Artery Disease Cohort
EGAD00010000236 | EGA
GenomicsTrachoma_GWAS_Unscarred_Controls
Gambian specimens with trachomatous scarring WHO grade C2/C3
EGAD00010000940 | EGA
GenomicsTrachoma_GWAS_Scarred_Cases
Gambian specimens without trachomatous scarring
EGAD00010000941 | EGA
GenomicsWellcome Trust Sanger Institute Data Sharing Policy for Trachoma GWAS
Data Access Committee EGAC00001000489
EGAC00001000489 | EGA
Genomicsena-DATASET-IGMM-28-09-2016-11:49:17:763-561 - samples
Exome sequencing of isolate populations and Generation Scotland
EGAD00001002715 | EGA
GenomicsHomozygous loss-of-function variants in European cosmopolitan and isolate populations
Homozygous loss of function (HLOF) variants provide a valuable window on gene function in humans, as well as an inventory of the human genes that are not essential for survival and reproduction. All humans carry at least a few HLOF variants, but the exact number of inactivated genes that can be tole...
EGAS00001001606 | EGA
GenomicsQTL-DAC
Data Access Committee EGAC00001000063
EGAC00001000063 | EGA
Sort   by:  
 Page size