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TranscriptomicsTranscription profiling by array of 4T1 murine breast carcinoma cells and derived cell lines resistant to photodynamic therapy induced by novel porphyrin-based photosensitizers and temoporfin
The efficacy of photodynamic therapy for treating premalignant and malignant tumors is often limited by the emerging resistant tumor cells. We have developed experimental model systems to study the mechanisms associated with resistance to photodynamic therapy induced by structurally similar photosen...
ORGANISM(S): Mus musculus 
2017-06-14 | E-MTAB-5082 | biostudies-arrayexpress
TranscriptomicsModification of Disp3 expression levels by CRISPR/Cas9 technology affects neural stem cells capacity to differentiate.
DISP3 (PTCHD2), a sterol-sensing domain-containing protein, is highly expressed in neural tissue but its role in neural differentiation is unknown. To determine the effect of DISP3 on neural stem cells phenotype of NS-5 cells, we impaired Disp3 gene using CRISPR/Cas9 technology. Modification of Disp...
ORGANISM(S): Mus musculus 
2017-02-17 | E-MTAB-4485 | biostudies-arrayexpress
Transcriptomicsc-Myb inhibits myoblast fusion
The study of the effects of modification of c-Myb expression on differenatiation of C2C12 cells
ORGANISM(S): Mus musculus 
2013-10-21 | E-MTAB-1376 | biostudies-arrayexpress
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