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MetabolomicsHuman basal cell carcinoma samples analysed by laser desorption rapid evaporative ionisation mass spectrometry (LD-REIMS) imaging

Laser ablation rapid evaporative ionisation mass spectrometry (LA-REIMS) was used to analyse human basal cell carcinoma (BCC) samples. 14 samples are presented here, along with H&E-stained histological images.

2025-07-28 | MTBLS12786 | MetaboLights
MetabolomicsThe gut microbiota influence the basal physiological parameters in equine athletes
Not available
ORGANISM(S): Equus caballus 
ST000945 | MetabolomicsWorkbench
TranscriptomicsLong-noncoding RNAs in basal cell carcinoma
A total of 3 patients with basal cell carcinoma (BCC) and 3 healthy individuals (control; non-lesional skin) were enrolled in the study. Punch biopsies (4 mm) were obtained under local anaesthesia and immediately put in RNAlater (Qiagen, Hilden, Germany) and stored at - 80 °C until RNA extraction. ...
ORGANISM(S): Homo sapiens 
2016-03-29 | E-GEOD-74858 | biostudies-arrayexpress
TranscriptomicsFibroblasts prepared from stroma of basal cell carcinoma in comparison to normal dermal fibroblasts
Adult tissue stem cells are known to participate in cancer formation. Indeed, cells exhibiting markers of embryonic stem cells such as Oct-4 and Nanog were detected in some malignant tumors. In this study we demonstrated that stromal cells prepared from the basal cell carcinoma are able to induce ex...
ORGANISM(S): Homo sapiens 
2011-11-02 | E-MTAB-272 | biostudies-arrayexpress
TranscriptomicsEZH2 promotes a bi-lineage identity in basal-like breast cancer cells
The mechanisms regulating breast cancer differentiation state are poorly understood. Of particular interest are molecular regulators controlling the highly aggressive and poorly differentiated traits of basal-like breast carcinomas. Here we show that the Polycomb factor EZH2 maintains the differenti...
ORGANISM(S): Homo sapiens 
2012-09-21 | E-GEOD-36939 | biostudies-arrayexpress
TranscriptomicsThe retinoblastoma gene is targeted for rearrangements in BRCA1-deficient basal-like breast cancer.
Breast tumors from BRCA1 germ line mutation carriers typically exhibit features of the basal-like molecular subtype. However, the specific genes recurrently mutated as a consequence of BRCA1 dysfunction have not been fully elucidated. In this study, we utilized gene expression profiling to molecular...
ORGANISM(S): Homo sapiens 
2012-06-26 | E-GEOD-25307 | biostudies-arrayexpress
TranscriptomicsCAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer
This SuperSeries is composed of the following subset Series: GSE12811: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (expr) GSE12813: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (aCGH) Refer to in...
ORGANISM(S): Homo sapiens 
2009-09-08 | E-GEOD-12827 | biostudies-arrayexpress
TranscriptomicsCorrelation of global micro RNA expression with basal cell carcinoma subtype
Basal cell carcinomas (BCCs) are the most common cancers in the US. Histologic appearance distinguishes several subtypes, each of which can have a different biologic behavior. In this study global miRNA expression was quantified by high throughput sequencing in nodular BCCs, a subtype that is slow...
ORGANISM(S): Homo sapiens 
2012-02-01 | E-GEOD-33665 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of microRNA expression in basal cell carcinoma
Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC (n=7) were included in the study. Punch biop...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-34535 | biostudies-arrayexpress
TranscriptomicsCAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (expr)
Title: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer Summary: Breast cancer exhibits clinical and molecular heterogeneity, where expression-profiling studies have identified five major molecular subtypes. The basal-like subtype, expressing basal e...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-12811 | biostudies-arrayexpress
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