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TranscriptomicsResponse of IRF7-deficient peripheral blood mononuclear cells to pH1N1 influenza virus infection
IRF7 plays a critical role in the production and amplification of the antiviral type I and III interferon response. Autosomal recessive IRF7-deficiency resulted in life-threatening influenza disease in a 3-year-old child. We studied the impact of IRF7-deficiency in non-hematopoietic tissues (fibrobl...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-66486 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of A549 cells treated with XRN2 siRNA under basal conditions
Untransfected (no siRNA), control siRNA or XRN2 siRNA treated A549 cells were analyzed for gene expression differences under basal conditions 3 Biological Replicates per condition
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-66662 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of A549 cells treated with SETX siRNA under basal conditions
Untransfected (no siRNA), control siRNA or SETX siRNA treated A549 cells were analyzed for gene expression differences under basal conditions 3 Biological Replicates per condition
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-52933 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of A549 cells treated with Xrn2 siRNA upon Influenza A/PR/8/34(ΔNS1) Infection
Untransfected (no siRNA), control siRNA or Xrn2 siRNA treated A549 cells were infected with A/Puerto Rico/8/1934(ΔNS1) for 4 hours 3 Biological Replicates per condition
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-66661 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression profiles of A549 cells treated with SETX siRNA upon Influenza A/PR/8/34(ΔNS1) Infection
Untransfected (no siRNA), control siRNA or SETX siRNA treated A549 cells were infected with A/Puerto Rico/8/1934(ΔNS1) for 4 hours 3 Biological Replicates per condition
ORGANISM(S): Homo sapiens 
2015-03-30 | E-GEOD-52932 | biostudies-arrayexpress
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