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TranscriptomicsMobile 24 nt small RNAs direct transcriptional gene silencing in the root meristems of Arabidopsis thaliana
We grafted Transcriptional Gene Silencing (TGS)-inducing wild type Arabidopsis and a mutant that is compromised in 24 nucleotide (nt) small RNA (sRNA) production onto a wild type reporter line. We observed that 21-24 nt sRNAs were transmitted across a graft union yet only the 24 nt sRNAs directed RN...
ORGANISM(S): Arabidopsis thaliana 
2011-10-23 | E-GEOD-31651 | biostudies-arrayexpress
UnknownAdjuvant versus neoadjuvant chemotherapy in triple-negative breast cancer patients with BRCA mutations.
Not available
S-EPMC5994186 | biostudies-literature
Transcriptomicssmall RNAs sequences from grafted Arabidopsis thaliana and Nicotiana benthamiana tissues
A silencing signal in plants with an RNA specificity determinant moves through plasmodesmata and the phloem. To identify the mobile RNA we grafted Arabidopsis thaliana shoots to roots that would be a recipient for the silencing signal. Using high throughput sequencing as a sensitive detection method...
ORGANISM(S): Arabidopsis thaliana 
2010-03-24 | E-GEOD-20663 | biostudies-arrayexpress
GenomicsNGS data of Nicotiana benthamiana 16c plants after CRISPR/Cas9 gene editing
Provided data came from a detailed study on Nicotiana benthamiana 16c plants where we use Tobacco Rattle Virus (TRV) as a molecular switch to change the chromatin state of a reporter gene (P35S::GFP) from an actively transcribed to a transcriptionally silenced state. Our approach enables us to inter...
ORGANISM(S): Nicotiana benthamiana 
2022-05-04 | E-MTAB-10256 | biostudies-arrayexpress
TranscriptomicsA genome-wide CRISPR library for high-throughput genetic screening in Drosophila cells
Analysis of sgRNA sequences in the raw library and at different time points after transfection into S2R+ cells Two biological repeats of all samples at three timepoints post transfection, with three dilutions of library transfected.
ORGANISM(S): Drosophila melanogaster 
2015-04-01 | E-GEOD-67339 | biostudies-arrayexpress
TranscriptomicsRNAi profiling by array of Drosophila S2 cells with RNAi knock down of NURK subunits and TTK69 transcription factor
RNAi knockdown of NURD subunits: MI2/CG8103, MEP1/CG1244, MTA1-like/CG2244; and TTK69 transcription factor
ORGANISM(S): Drosophila melanogaster 
2010-07-01 | E-TABM-1010 | biostudies-arrayexpress
UnknownMonomeric tau uptake by human neurons depends on receptor LRP1 and kinase LRRK2
Not available
S-SCDT-10_1038-S44318-025-00514-0 | biostudies-other
UnknownChallenge of cardiovascular prevention in primary care: achievement of lifestyle, blood pressure, lipids and diabetes targets for primary prevention in England - results from ASPIRE-3-PREVENT cross-sectional survey.
Not available
S-EPMC11481111 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
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