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TranscriptomicsGene expression networks in COPD: microRNA and mRNA regulation
70 miRNAs and 2667 mRNAs were differentially expressed between lung tissue from subjects with COPD and smokers without COPD. miRNA and mRNA expression profiles enriched for biological pathways that may be relevant to the pathogenesis of COPD including the transforming growth factor b, Wnt and focal ...
ORGANISM(S): Homo sapiens 
2012-06-26 | E-GEOD-38974 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiles of interstitial lung disease (ILD) patients
The mechanisms and molecular pathways underlying interstitial lung diseases (ILDs) are poorly understood. Systems biology approaches were used to identify perturbed networks in these disease states to gain a better understanding of the underlying mechanisms of disease. Through profiling genes and mi...
ORGANISM(S): Homo sapiens 
2011-04-19 | E-GEOD-21394 | biostudies-arrayexpress
TranscriptomicsMacrophage Microvesicles Induce Macrophage Differentiation and miR-223 Transfer
Microvesicles (MV) are small membrane-bound particles comprised of exosomes and various sized extracellular vesicles. These are released by a number of cell types. Microvesicles have a variety of cellular functions from communication to mediating growth and differentiation. Microvesicles contain pro...
ORGANISM(S): Homo sapiens 
2013-03-08 | E-GEOD-41889 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of interstitial lung disease (ILD) patients
The mechanisms and molecular pathways underlying interstitial lung diseases (ILDs) are poorly understood. Systems biology approaches were used to identify perturbed networks in these disease states to gain a better understanding of the underlying mechanisms of disease. Through profiling genes and mi...
ORGANISM(S): Homo sapiens 
2011-03-24 | E-GEOD-21369 | biostudies-arrayexpress
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