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GenomicsGenome-wide mutation analysis of germinal-center B-cell derived lymphomas within the ICGC MMML-Seq Consortium
Germinal-center B-cell derived lymphomas (GCB-lymphomas) are the most common B-cell lymphomas in children and adults, with Burkitt Lymphomas (BL) predominating in childhood and follicular lymphoma (FL) and diffuse large B-cell lymphomas (DLBCL) predominating in older age groups. The cell-of-origin i...
EGAS00001000394 | EGA
GenomicsBIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues
C-MYC (henceforth MYC) is one of the most frequently overexpressed oncogenes in human cancer and even modestly deregulated MYC expression can initiate ectopic proliferation in many post-mitotic, terminally differentiated cell types in vivo. Metazoan organisms have consequently evolved a number of me...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-59001 | biostudies-arrayexpress
ProteomicsSuper-paramagnetic iron oxide nanoparticles reprogram the tumor microenvironment and reduce lung cancer growth
Tumor associated macrophages (TAMs) are known to play a role in a multitude of processes that facilitate lung cancer growth, including the suppression of tumoricidal immune activation and the absorption of chemotherapeutics. Therefore, deciphering new therapies to reprogram TAMs towards an anti-tumo...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-18 | PXD040145 | Pride
Macrophages Immunotherapy Spion Iron Lung cancer 
UnknownSafety and Efficacy of Toripalimab in Patients with Cholangiocarcinoma: An Open-Label, Phase 1 Study.
Not available
S-EPMC11728388 | biostudies-literature
UnknownA First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas.
Not available
S-EPMC10022862 | biostudies-literature
ProteomicsIdentification of human beta-2 microglobulin in bronchoalveolar lavage
The uploaded data is related to the identification of beta-2-microglobulin isolated from bronchoalveolar lavage. The sample was digested with trypsin and the proteolytic fragments were identified by MS/MS
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-12-15 | MSV000086602 | MassIVE
UnknownSpecific allelic variants of SNPs in the MDM2 and MDMX genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients.
Not available
S-EPMC6443004 | biostudies-literature
GenomicsWGSeq_HealthyHuman_DATA_SET_xmas_MB_2013_07_10 - samples
HSC73_clone: Bone marrow mononuclear cells from the healthy 73 years old female were thawed and labeled with Alexa-Fluor 488-conjugated anti-CD34 (581, Biolegend), Alexa-Fluor 700-conjugated anti-CD38 (HIT2, eBioscience), a cocktail of APC-conjugated lineage antibodies consisting of anti-CD4 (RPA-T4...
EGAD00001000666 | EGA
GenomicsWGSeq_PreMalignant_DATA_SET_xmas_MB_2013_07_10 - samples
Illumina HiSeq sequence data (with >30x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. Sample derived from secondary myelodysplastic syndrome (MDS...
EGAD00001000665 | EGA
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-13:02:22:609-63 - samples
This dataset contains paired fastq files for LMS tumor samples
EGAD00001003828 | EGA
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