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TranscriptomicsMicroRNA expression profiling of Ewing sarcoma cell lines upon TARBP2 depletion
We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem c...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-31144 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of Ewing sarcoma spheres vs. adherent cells
We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem c...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-31145 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of Ewing sarcoma cancer stem cells
We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem c...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-30513 | biostudies-arrayexpress
MetabolomicsComprehensive systems biology analysis of a seven-month cigarette smoke inhalation study in C57BL/6 mice
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of smoke derived from a prototype modified risk tobacco product (pMRTP) as compare...
2015-11-19 | MTBLS143 | MetaboLights
TranscriptomicsIn vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells.
Cigarette smoke causes diseases such as cardiovascular disorders. Heating tobacco, instead of burning, reduces consistently the amount of toxic compounds and may exert a reduced impact on cardiovascular health compared to cigarettes. Aqueous extract from the aerosol of a potential modified risk toba...
ORGANISM(S): Homo sapiens 
2018-08-09 | E-MTAB-6721 | biostudies-arrayexpress
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