Sort   by:  
 Page size 
TranscriptomicsImmune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-05-08 | E-GEOD-57343 | biostudies-arrayexpress
TranscriptomicsPolycomb CBX7 represses expression of tumor suppressor genes
Polycomb CBX7 was stably expressed in embryonal carcinoma cells in order to identify target genes. The study was specifically geared toward unveiling gene targets that are susceptible to DNA hypermethylation in adult cancer. A number of CBX7 target tumor suppressor genes were thereby identified an...
ORGANISM(S): Homo sapiens 
2009-09-23 | E-GEOD-10541 | biostudies-arrayexpress
TranscriptomicsCancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells (methylation data)
he ability to induce pluripotent stem cells from committed, somatic human cells provides tremendous potential for regenerative medicine. However, there is a defined neoplastic potential inherent to such reprogramming that must be understood and may provide a model for understanding key events in tum...
ORGANISM(S): Homo sapiens 
2011-06-16 | E-GEOD-29872 | biostudies-arrayexpress
TranscriptomicsCancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells (expression data)
The ability to induce pluripotent stem cells from committed, somatic human cells provides tremendous potential for regenerative medicine. However, there is a defined neoplastic potential inherent to such reprogramming that must be understood and may provide a model for understanding key events in tu...
ORGANISM(S): Homo sapiens 
2011-06-16 | E-GEOD-29870 | biostudies-arrayexpress
TranscriptomicsConvergence of Mutation and Epigenetic Alterations Identifies Common Target Genes in Breast and Colon Cancer
The identification and characterization of tumor suppressor genes has enhanced our understanding of the biology of cancer and enabled the development of new diagnostic and therapeutic modalities. Whereas in past decades, a handful of tumor suppressors have been slowly identified using techniques su...
ORGANISM(S): Homo sapiens 
2009-09-23 | E-GEOD-10613 | biostudies-arrayexpress
TranscriptomicsEffect of AZA on gene expression of multiple breast, colon, and ovarian cell lines [expression]
Epigenetic therapy is emerging as a potential therapy for solid tumors. To investigate its mechanism of action, we performed integrative expression and methylation analysis of 63 cancer cell lines (breast, colorectal, and ovarian) after treatment with the DNA methyltransferase inhibitor 5-azacitidin...
ORGANISM(S): Homo sapiens 
2014-05-08 | E-GEOD-57341 | biostudies-arrayexpress
TranscriptomicsImmune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers [methylation]
Epigenetic therapy is emerging as a potential therapy for solid tumors. To investigate its mechanism of action, we performed integrative expression and methylation analysis of 63 cancer cell lines (breast, colorectal, and ovarian) after treatment with the DNA methyltransferase inhibitor 5-azacitidin...
ORGANISM(S): Homo sapiens 
2014-05-08 | E-GEOD-57342 | biostudies-arrayexpress
UnknownThe landscape of viral associations in human cancers.
Not available
S-EPMC8076016 | biostudies-literature
UnknownIntegrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma.
Not available
S-EPMC5964983 | biostudies-literature
Sort   by:  
 Page size