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ProteomicsProteomic Ligandability Maps of Phosphorus(V) Stereoprobes Identify Covalent TLCD1 Inhibitors
Activity-based protein profiling (ABPP) of stereoisomerically defined sets of electrophilic compounds (‘stereoprobes’) offers a versatile way to discover covalent ligands for proteins in native biological systems. Here we report the synthesis and chemical proteomic characterization of stereoprobes b...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD060339 | Pride
Lipid biology Chemical biology Chemical proteomics Electrophilic probes 
UnknownPru du 1, the Bet v 1-homologue from almond, is a major allergen in patients with birch pollen associated almond allergy.
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S-EPMC9358727 | biostudies-literature
UnknownProteomic Ligandability Maps of Phosphorus(V) Stereoprobes Identify Covalent TLCD1 Inhibitors.
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S-EPMC11838393 | biostudies-literature
UnknownRibosome biogenesis-based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer: translational study from the VICTORIA trial in collaboration with the GINECO group.
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S-EPMC9812831 | biostudies-literature
UnknownSafety and Efficacy of the mTOR Inhibitor, Vistusertib, Combined With Anastrozole in Patients With Hormone Receptor-Positive Recurrent or Metastatic Endometrial Cancer: The VICTORIA Multicenter, Open-label, Phase 1/2 Randomized Clinical Trial.
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S-EPMC9100474 | biostudies-literature
UnknownAgave angustifolia Haw. Leaves as a Potential Source of Bioactive Compounds: Extraction Optimization and Extract Characterization.
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S-EPMC10935067 | biostudies-literature
UnknownReversible Plastic Deformation of Polymer Blends as a Means to Achieve Stretchable Organic Transistors.
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S-EPMC5497511 | biostudies-literature
UnknownAqueous asymmetric pseudocapacitor featuring high areal energy and power using conjugated polyelectrolytes and Ti3C2Tx MXene.
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S-EPMC12381132 | biostudies-literature
UnknownDnmA and FisA Mediate Mitochondria and Peroxisome Fission, and Regulate Mitochondrial Function, ROS Production and Development in Aspergillus nidulans.
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S-EPMC7232558 | biostudies-literature
UnknownOrder enables efficient electron-hole separation at an organic heterojunction with a small energy loss.
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S-EPMC5773693 | biostudies-literature
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