Bcl-2-like - OmicsDI

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Transcriptomics (1339)
Unknown (883)
Genomics (112)
Proteomics (28)
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Organisms

Homo sapiens (592)
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Arabidopsis thaliana (26)
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Caenorhabditis elegans (8)
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Organisms

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Repository

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Disease

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Instrument Platform

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UNIPROT ID/AC

P48436 (1)
Q15797 (1)
Q14457 (1)
P37023 (1)
Q9UNA0 (1)
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P45452 (1)
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CHEBI ID

CHEBI:26523 (1)
CHEBI:141364 (1)
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CHEBI:138394 (1)
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CHEBI:71172 (1)
CHEBI:34485 (1)
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CHEBI:43580 (1)
CHEBI:73858 (1)
CHEBI:28683 (1)
CHEBI:16359 (1)
CHEBI:27897 (1)
CHEBI:16990 (1)

Metabolite Name

Histidine (2)
Leucine (2)
Glycine (2)
LysoPC (LPC) (17:0/0:0) (1)
LysoPC (LPC) (18:1(11Z)/0:0) (1)
LysoPC (LPC) (18:0/0:0) (1)
LysoPC (LPC) (16:0/0:0) (1)
LysoPC (LPC) (0:0/16:0) (1)
LysoPC (LPC) (18:2(9Z,12Z)) (1)
Cholic Acid (Dimer—no parent) (CA) (1)
Biliverdin (BLD) (1)
3-oxocholic acid -H2O (OCA) (1)
(9Z,12Z)-(8R)-8-Hydroperoxyoctadeca-9,12-dienoic acid (HPODE) (1)
Bilirubin (BR) (1)
N-[(3alpha,5beta,12alpha)-3,12-Dihydroxy-7,24-dioxocholan-24-yl]glycine (NDGCA) (1)
3-indolepropionic acid (3IPA) (1)
Enterolactone (EL) (1)
Hexahydrohippurate (HHA) (1)
N-(cyclohex-1-en-1-ylcarbonyl)glycine (NCG) (1)
N-Methylhippuric Acid (NMHA) (1)
Ureidoglutaric acid (1)
Pectin (Galacturonic acid) (1)
N,n-dimethylaniline (1)
N-.gamma.-acetyl-n-2-formyl-5-methoxykynurenamine (1)
Cis-jasmone (1)
Cis-10-nonadecenoic acid (1)
Butyl 4-hydroxybenzoate (1)
Benzoic acid eugenyl ester (1)
4-methoxy-6-[2-(4-methoxyphenyl)ethyl]pyran-2-one (1)
12-oxo-5z,8z,10e,14z-eicosatetraenoic acid (1)

IsPrivate

False (1)

First Public Date

2025 (11)
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2015 (4)
2014 (4)
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Modelling Approach

Ordinary differential equation model (1)

Study type

Transcription profiling by array (983)
Unknown experiment type (96)
Comparative genomic hybridization by array (60)
RNA-seq of coding RNA (51)
ChIP-seq (30)
ChIP-chip by array (22)
Methylation profiling by array (22)
Other (17)
RNA-seq of coding RNA from single cells (12)
RNA-seq of total RNA (7)
RNA-seq of non coding RNA (6)
MicroRNA profiling by array (5)
Proteomic profiling by array (5)
Genotyping by array (4)
RNAi profiling by array (3)
Transcription profiling by RT-PCR (3)
DNA-seq (3)
Transcription profiling by SAGE (2)
ChIP-chip by tiling array (2)
Cell line - High-throughput sequencing (2)
Hi-C (2)
Human - High-throughput sequencing (1)
Cell line - One-color microarray (1)
MicroRNA profiling by high throughput sequencing (1)
Bisulfite-seq (1)
ATAC-seq (1)
RIP-seq (1)
Genotyping by high throughput sequencing (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2010 (340)
2011 (164)
2014 (163)
2012 (159)
2013 (158)
2015 (117)
2008 (108)
2009 (99)
2016 (97)
2022 (94)
2021 (86)
2025 (85)
2024 (81)
2023 (77)
2020 (73)
2007 (65)
2019 (58)
2018 (58)
2017 (48)
2006 (29)
2026 (19)
2005 (18)
2004 (18)
2003 (10)
2000 (5)
2002 (3)
2001 (2)
1999 (2)
1997 (1)
1996 (1)

Lab affiliation

Associate Professor of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, IN (1)
Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Rutgers Biomedical and Health Sciences (1)
Dipartimento di Scienze Chimiche, Farmaceutiche ed Agrarie, Università degli Studi di Ferrara (1)
Max Perutz Labs, Medical University of Vienna, Vienna BioCenter (1)
Northeastern University (1)
Proteomics and Metabolomics research program, Basic research department, Children’s Cancer Hospital 57357, Cairo, Egypt (1)
St. Jude Children's Research Hospital (1)

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Transcription profiling of human SCLC cell line set 2

RNA expression analysis was performed to compare patterns to sensitivity to BCL2 inhibitors (ABT-263). Overexpression of the prosurvival Bcl-2 family members (Bcl-2, Bcl-xL and Mcl-1) is commonly associated with tumor maintenance, progression and chemoresistance. We previously reported the discover...

ORGANISM(S): Homo sapiens

2008-06-19 | E-GEOD-10841 | biostudies-arrayexpress

Telomerase Reverse Transcriptase Contains a BH3-Like Motif and Interacts with BCL-2 Family Members.

Not available

S-EPMC6078858 | biostudies-literature

Intracellular insulin-like growth factor-1 induces Bcl-2 expression in airway epithelial cells.

Not available

S-EPMC3359962 | biostudies-literature

Bcl-2-like protein-10 increases aggressive features of melanoma cells.

Not available

S-EPMC9400776 | biostudies-literature

Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis.

Not available

S-EPMC2494871 | biostudies-literature

Bcl-2 inhibition combined with PPARα activation synergistically targets leukemic stem cell-like cells in acute myeloid leukemia.

Not available

S-EPMC10465498 | biostudies-literature

BAD BioID in 2D MCF10A cell culture

BioID proximity labeling experiment on Bcl2-associated agonist of cell death (BAD) using BAD-miniTurbo stable cell line in MCF10A, 2D cell culture. Sample: BAD-turbo-biotin; controls: BAD-biotin, turbo-biotin, BAD-turbo (n=3).

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2023-11-10 | MSV000093357 | MassIVE

The IκB-protein BCL-3 controls Toll-like receptor-induced MAPK activity by promoting TPL-2 degradation in the nucleus.

Not available

S-EPMC6926074 | biostudies-literature

A poxvirus Bcl-2-like gene family involved in regulation of host immune response: sequence similarity and evolutionary history.

Not available

S-EPMC2907574 | biostudies-literature

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2.

Not available

S-EPMC5295441 | biostudies-literature