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Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia We report two novel, cryptic chromosomal abnormalities in precursor B-cell acute lymphoblastic leukemia (BCP-ALL): a translocation, either t(X;14)(p22;q32)...
ORGANISM(S): Homo sapiens 
Targeted RNA-seq of BCP-ALL pediatric patients
Whole transcriptome analysis to detect fusion genes in pediatric BCP-ALL
Targeted RNA-seq of pediatric infant (<1year of age at diagnosis) patients affected by B-cell precursor Acute Lymphoblastic leukemia (BCP-ALL). The aim of the study is to identify fusion gene rearrangements involved in childhood leukemia, using a custom targeted panel for RNA analysis by NGS.
ORGANISM(S): Homo sapiens 
CRISPR-engineered MLL-AF4 BCP-ALL
Whole transcriptome RNA-seq of pediatric infant (<1year of aget at diagnosis) patients affected by B-cell precursor Acute Lymphoblastic leukemia (BCP-ALL). The aim of the study is to identify fusion gene rearrangements involved in childhood leukemia, using Next Generation Sequencing (NGS)
ORGANISM(S): Homo sapiens 
Primary xenografts were made from a variety of different high-risk childhood BCP-ALL leukemia samples.
ORGANISM(S): Homo sapiens 
2015-03-05 | GSE58290 | GEO
RNA-seq data of NKX6-3 knockdown in the BCP-ALL cell line RCH-ACV
A brain organoid/ALL co-culture model reveals the AP-1 pathway as critically associated with CNS-involvement of BCP-ALL
A brain organoid/ALL co-culture model reveals the AP-1 pathway as critically associated with CNS involvement of BCP-ALL
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