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MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS674 | MetaboLights
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
UnknownSingle-cell transcriptomic-informed deconvolution of bulk data identifies immune checkpoint blockade resistance in urothelial cancer.
Not available
S-EPMC11133924 | biostudies-literature
GenomicStudy of Irish Amyotrophic Lateral Sclerosis (SIALS)

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of motor neurons. Epidemiological studies indicate that 2-5% of cases are familial, usually with an autosomal dominant pattern of inheritance. For a portion of these, causative genes have been...

phs000127 | dbGaP
UnknownNKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer.
Not available
S-EPMC9479122 | biostudies-literature
UnknownHLA-E and NKG2A Mediate Resistance to <i>M. bovis</i> BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer.
Not available
S-EPMC11398371 | biostudies-literature
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