Sort   by:  
 Page size 
ProteomicsProteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells
SUMOylation is a form of post-translational modification involving covalent attachment of SUMO (Small Ubiquitin-like Modifier) polypeptides to specific lysine residues in the target protein. In human cells, there are four SUMO proteins, SUMO1–4, with SUMO2 and SUMO3 forming a closely related subfami...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080699 | MassIVE
TranscriptomicsRNA-seq on S. cerevisiae YPH499 with or without induced methylation
Effect of induced Methylation on Gene expression in yeast. Total RNA from a control strain and a strain expressing the 4 murine DNMTs were extracted and sequenced in a hiseq 4000
ORGANISM(S): Saccharomyces cerevisiae 
2020-09-30 | E-MTAB-9195 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of zebrafish embryos after 96 h exposure to two subsequent concentrations of 4-methyl-3-deoxy-1,9,12-trihydroxyestra-1,3,5(10)7-tetraene-6,17-dione (MDTETD) and 12β-trihydroxy-androsta-4,6-diene-3,17-dione (THADD)
The aim of this mRNA expression profiling experiment was to screen for ecotoxicogenomic fingerprints in zebrafish (Danio rerio) embryos as aquatic vertebrate non-target model exposed to sublethal concentrations of 4-methyl-3-deoxy-1,9,12-trihydroxyestra-1,3,5(10)7-tetraene-6,17-dione (MDTETD) and 12...
ORGANISM(S): Danio rerio 
2021-10-11 | E-MTAB-10922 | biostudies-arrayexpress
TranscriptomicsDynamic transcriptome analysis reveals mRNA synthesis and decay in yeast
To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non-perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA was used to monitor the cellular response to osmotic stress in comparison to the wild type. Genomic occupa...
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-01 | E-MTAB-439 | biostudies-arrayexpress
TranscriptomicsAnalysis of Spt16 depletion
Transcription rate analysis in Yeast by means of GRO, mRNA amount and ChIP-on-chip during the depletion of Spt16p. Keywords: Genomic run-on GRO ChIP-chip Transcription rate analysis by means of GRO and mRNA amount (RA) of three independent replicates during the depletion of Spt16p (Control and 5 &...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-14082 | biostudies-arrayexpress
Transcriptomicsrec-Y2H matrix in S. cerevisiae screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
RNA-binding proteins (RBPs) are crucial factors of post-transcriptional gene regulation and their modes of action are intensely investigated. At the center of attention are RNA motifs that guide where RBPs bind. However, sequence motifs recognized by RBPs are typically a poor predictor of RBP-RNA in...
ORGANISM(S): Saccharomyces cerevisiae 
2021-09-01 | E-MTAB-9612 | biostudies-arrayexpress
TranscriptomicsGene category-specific regulation of transcription elongation across the yeast genome
Analysis of genome-wide differences of transcription using Genomic run-on (GRO), RNApol II ChIP-on-Chip, cDNA analysis and ChIP-on-Chip. This SuperSeries is composed of the following subset Series: GSE14060 RNA pol II ChIP on chip (RPCC) GSE14077 RPCC analysis of rap1-sil, tpk1 & tpk2 GSE14080 ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-14084 | biostudies-arrayexpress
GenomicsWhole genome sequence for S. cerevisiae isolates.
Aim of this project is to identify biomarkers associated with fungal persistence in the host and genomic variability among strains isolated from different environments.
ORGANISM(S): Saccharomyces cerevisiae 
2016-04-30 | E-SYBR-8 | biostudies-arrayexpress
GenomicsDNA-seq of various fungi isolated from faecal materials and environmental samples for comparative genomic analyses, SYBARIS project
Aim of this project is to perform a comparative genomic study (including all S. cerevisiae sequenced and available) of the variability and evolutionary traits of yeast.
ORGANISM(S): Saccharomyces cerevisiae 
2016-04-30 | E-SYBR-12 | biostudies-arrayexpress
TranscriptomicsOptimization of codon translation rates via tRNA modifications maintains proteome integrity
Proteins begin to fold as they emerge from translating ribosomes. The kinetics of ribosome transit along a given mRNA can influence nascent chain folding, but the extent to which individual codon translation rates impact proteome integrity remains unknown. Here, we show that slower decoding of discr...
ORGANISM(S): Caenorhabditis elegans 
2015-06-04 | E-GEOD-67387 | biostudies-arrayexpress
Sort   by:  
 Page size