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TranscriptomicsGenome wide methylation array analysis in T-ALL
In short: Genome wide promoter DNA methylation profiling of 43 T-ALL samples and 5 T-cell controls (normal bone marrow and stimulated T-cells) . The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Manuscript abst...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-42079 | biostudies-arrayexpress
TranscriptomicsGenome wide gene expression array analysis in T-ALL
In short: The objective with the gene expression array (Illumina HT-12 v.4) analysis of 17 T-ALL samples was to correlate gene expression levels with DNA promoter methylation status. Manuscript Abstract: Background: Treatment of pediatric T-cell acute lymphoblastic leukemia (T-ALL) has improved, but...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-41621 | biostudies-arrayexpress
UnknownSoft Tissue Tumor with PAK2::RAF1 Kinase Fusion: An Emerging Sarcoma Entity.
Not available
S-EPMC11521462 | biostudies-literature
TranscriptomicsAffymetrix SNP-array data for 2 ETV6/RUNX1-positive Acute Lymphoblastic Leukemia samples and corresponding normal samples
Acute lymphoblastic leukemia (ALL), the most common malignant disorder in childhood, is typically associated with numerical chromosomal aberrations, fusion genes or small focal deletions, thought to represent important pathogenetic events in the development of the leukemia. Mutations, such as single...
ORGANISM(S): Homo sapiens 
2012-07-02 | E-GEOD-25116 | biostudies-arrayexpress
UnknownGenetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
Not available
S-EPMC3003126 | biostudies-literature
TranscriptomicsIllumina SNP-array data for 2 ETV6/RUNX1-positive Acute Lymphoblastic Leukemia samples and corresponding normal samples
Acute lymphoblastic leukemia (ALL), the most common malignant disorder in childhood, is typically associated with numerical chromosomal aberrations, fusion genes or small focal deletions, thought to represent important pathogenetic events in the development of the leukemia. Mutations, such as single...
ORGANISM(S): Homo sapiens 
2012-07-02 | E-GEOD-25102 | biostudies-arrayexpress
UnknownSingle base substitution mutational signatures in pediatric acute myeloid leukemia based on whole genome sequencing.
Not available
S-EPMC8102186 | biostudies-literature
UnknownPromoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia.
Not available
S-EPMC3675104 | biostudies-literature
UnknownGenetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.
Not available
S-EPMC4767471 | biostudies-literature
TranscriptomicsAffy SNP-array data for 23 ETV6/RUNX1-positive ALL patient samples and one cell line
The ETV6/RUNX1 fusion gene, present in 25% of B-lineage childhood acute lymphoblastic leukemia (ALL), is thought to represent an initiating event, which requires additional genetic changes for leukemia development. To identify additional genetic alterations, 24 ETV6/RUNX1-positive ALLs were analyzed...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-19996 | biostudies-arrayexpress
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