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TranscriptomicsTranscription profiling of human glioma cell lines reveals CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and expression profiles
We cultured tumor cells from 22 GBM under medium conditions favoring the growth of neural stem cells. 11 out of 15 primary GBM contained a significant CD133+ subpopulation that comprised cells showing all hallmarks of neural stem cells. Cell lines derived from these CD133+ GBM showed a neurosphere-l...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-7181 | biostudies-arrayexpress
TranscriptomicsCharacterization of the HP1021 regulon of Helicobacter pylori
The genome of the gastric pathogen Helicobacter pylori harbors a remarkably low number of regulatory genes, including three and five open reading frames encoding two-component histidine kinases and response regulators, respectively, which are putatively involved in transcriptional regulation. Inacti...
ORGANISM(S): Helicobacter pylori 
2010-07-01 | E-GEOD-5971 | biostudies-arrayexpress
TranscriptomicsThe cell envelope stress response mediated by the LiaFSRLm three-component system of Listeria monocytogenes is controlled via the phosphatase activity of the bifunctional histidine kinase LiaSLm
Most members of the phylum Firmicutes harbor a two-component system, LiaSR, which is involved in the response to cell envelope stress elicited most notably by inhibitors of the lipid II cycle. In all LiaSR systems studied in detail LiaSR-mediated signal transduction was shown to be negatively contro...
ORGANISM(S): Listeria monocytogenes EGD-e 
2010-11-16 | E-GEOD-24107 | biostudies-arrayexpress
TranscriptomicsCharacterization of the ArsRS regulon of Helicobacter pylori
The human gastric pathogen Helicobacter pylori is extremely well adapted to the highly acidic conditions encountered in the stomach. The pronounced acid resistance of H. pylori relies mainly on the ammonia-producing enzyme urease, however, urease-independent mechanisms are likely to contribute to ac...
ORGANISM(S): Helicobacter pylori 
2010-07-01 | E-GEOD-4293 | biostudies-arrayexpress
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