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TranscriptomicsDSB formation in replication compromised cells
DSBs were mapped genome-wide by ssDNA enrichment in cdc6-mn replication comprimsied strains. We mapped DSB sites by detecting DSB-associated ssDNA enrichment on microarrays. To test the role of DNA replication in DSB formation, we mapped ssDNA in a cdc6-mn replication depleted strain. ssDNA was isol...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-18 | E-GEOD-35666 | biostudies-arrayexpress
TranscriptomicsSeparation of DNA replication from the assembly of break-competent meiotic chromosomes
The meiotic cell division reduces the chromosome number from diploid to haploid to form gametes for sexual reproduction. Although much progress has been made in understanding meiotic recombination and the two meiotic divisions, the processes leading up to recombination, including the prolonged pre-m...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-14 | E-GEOD-35667 | biostudies-arrayexpress
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