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Role of BEND3 in transcription repression
BEND3 safeguards pluripotency by repressing differentiation-associated genes
We have uncovered that BEND3 is a heterochromatin-associated protein that functions as a transcription repressor. Expression of BEND3 correlates with the state of pluripotency, with a significant decline in BEND3 levels in differentiated cells. Cells lacking BEND3 show defects in cell cycle progress...
ORGANISM(S): Homo sapiens 
2022-02-08 | GSE151235 | GEO
We have uncovered that BEND3 is a heterochromatin-associated protein that functions as a transcription repressor. Expression of BEND3 correlates with the state of pluripotency, with a significant decline in BEND3 levels in differentiated cells. Cells lacking BEND3 show defects in cell cycle progress...
ORGANISM(S): Homo sapiens 
2022-02-08 | GSE171091 | GEO
The effect of corticosterone treatment on the transcriptome of mouse brain endothelial bEnd3 cells
TGF-beta/Smads signaling plays important roles in vascular integrity. To identify potential Smad4 target genes in brain endothelial cells that control cerebrovascular integrity, the microarray assay was performed to compare the gene expression profiles of bEnd3 transfected with Smad4-siRNA and contr...
ORGANISM(S): Mus musculus 
A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation
TGF-beta/Smads signaling plays important roles in vascular integrity. To identify potential Smad4 target genes in brain endothelial cells that control cerebrovascular integrity, the microarray assay was performed to compare the gene expression profiles of bEnd3 transfected with Smad4-siRNA and contr...
ORGANISM(S): Mus musculus 
2011-04-17 | GSE15736 | GEO
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