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TranscriptomicsGene expression data of pHGG tumor samples
Pediatric high-grade gliomas (pHGGs) harboring the K27M mutation of H3F3A (histone H3.3) are characterized by global reduction of the repressive histone mark H3K27me3 and DNA hypomethylation. Analysis of K27M-induced changes on H3K27me3 occupancy and DNA methylation at differentially expresed genes ...
ORGANISM(S): Homo sapiens 
2014-05-14 | E-GEOD-49822 | biostudies-arrayexpress
UnknownNovel Adamantanyl-Based Thiadiazolyl Pyrazoles Targeting EGFR in Triple-Negative Breast Cancer.
Not available
S-EPMC6044684 | biostudies-literature
TranscriptomicsRNA expression data from primary neuroblastoma tumors
RNA expression profiles of 105 primary neuroblastomas derived from customized 4 x 44k oligonucleotide microarrays (Agilent Technologies). These profiles are part of an integrative study combining genomewide epigenetic profiles with transcriptome data of the same neuroblastoma cohort. Tumors were der...
ORGANISM(S): Homo sapiens 
2016-09-08 | E-GEOD-73517 | biostudies-arrayexpress
TranscriptomicsDNA methylation data from primary neuroblastoma tumors
Genome wide DNA methylation profiling of primary neuroblastomas. The Illumina 450k methylation array was used to obtain DNA methylation profiles across approximately 485,000 CpGs in 105 neuroblastomas. Tumors were derived from 40 low-risk, 9 intermediate-risk and 56 high-risk patients. Bisulphite c...
ORGANISM(S): Homo sapiens 
2016-09-08 | E-GEOD-73515 | biostudies-arrayexpress
Genomics2013-11-19-17-24-36-breez-MB-2013-10-18-Whole_exome_DNAseq_Medulloblastoma - samples
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. The whole exome sequencing data of 20 SHH medulloblastomas ...
EGAD00001000698 | EGA
GenomicsSHH medulloblastoma samples
Sequencing data of human SHH medulloblastoma samples
EGAS00001000607 | EGA
TranscriptomicsPIN6 and MYB57 in Arabidopsis thaliana nectaries
Transcriptome of three genotypes of Arabidopsis thaliana lateral nectaries from stage 14-15 flowering - one wild type, one pin-6 mutant, and one myb-57 mutant.
ORGANISM(S): Arabidopsis thaliana 
2012-07-30 | E-MTAB-4376 | biostudies-arrayexpress
GenomicsChIP-seq-based analysis of differential K27me3 coverage in neuroblastoma cell lines treated with epigenetic drugs
The impact of drugs inhibiting DNA methylation (5-aza-2'-deoxycytodine, DAC) and EZH2 (EPZ-6438) on H3K27me3 coverage was analyzed in two neuroblastoma cell lines. Parallel analyses investigated associated changes in RNA expression and DNA methylation. The neuroblastoma cell lines Be(2)-C and IMR5-7...
ORGANISM(S): Homo sapiens 
2016-09-08 | E-GEOD-80445 | biostudies-arrayexpress
UnknownNeuroradiological findings in GAA-FGF14 ataxia (SCA27B): more than cerebellar atrophy.
Not available
S-EPMC10889027 | biostudies-literature
UnknownQuantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal subregions in in vivo MRI: towards a harmonized segmentation protocol.
Not available
S-EPMC4387011 | biostudies-literature
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