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TranscriptomicsRNAi promotes heterochromatic silencing through replication-coupled release of RNA pol II (RNA seq)
Heterochromatin comprises tightly compacted repetitive regions of eukaryotic chromosomes. The inheritance of heterochromatin through mitosis requires RNA interference (RNAi), which guides histone modification during the DNA replication phase of the cell cycle. Here, we show that the alternating arra...
ORGANISM(S): Schizosaccharomyces pombe 
2011-07-21 | E-GEOD-30827 | biostudies-arrayexpress
GenomicsRNAi promotes heterochromatic silencing through replication-coupled release of RNA pol II (ChIP-seq)
Heterochromatin comprises tightly compacted repetitive regions of eukaryotic chromosomes. The inheritance of heterochromatin through mitosis requires RNA interference (RNAi), which guides histone modification 1 during the DNA replication phase of the cell cycle2. Here, we show that the alternating a...
ORGANISM(S): Schizosaccharomyces pombe 
2011-07-29 | E-GEOD-31016 | biostudies-arrayexpress
GenomicsT-cell factor 4 and β-catenin chromatin occupancies pattern zonal liver metabolism.
β-catenin signaling can be both a physiological and an oncogenic pathway in the liver. It controls compartmentalized gene expression, allowing the liver to ensure its essential metabolic function. It is activated by mutations in 20 to 40% of hepatocellular carcinomas with specific metabolic features...
ORGANISM(S): Mus musculus 
2014-01-18 | E-GEOD-35213 | biostudies-arrayexpress
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